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Influenza Vaccines clinical trials

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NCT ID: NCT01013675 Completed - Influenza Vaccines Clinical Trials

Immunogenicity and Safety of a Cell-derived Influenza Vaccine in Elderly

Start date: November 2009
Phase: Phase 2
Study type: Interventional

A controlled, double-blind study to determine the immunogenicity and safety of influenza cell derived vaccine in elderly subjects.

NCT ID: NCT00961337 Completed - Influenza Clinical Trials

Evaluation of a School-based Influenza Vaccination Program

Start date: October 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether inactivated influenza vaccines are effective to protect school children and their households from getting influenza infection and further prevent student's absenteeism.

NCT ID: NCT00718120 Completed - Influenza Vaccines Clinical Trials

Immunogenicity and Safety Study of GSK Biologicals' Fluviral® (2008 - 2009 Season) in Adults Over 18 Years

Start date: July 18, 2008
Phase: Phase 3
Study type: Interventional

This study will evaluate the immunogenicity and safety of GSK Biologicals' Trivalent split virion influenza vaccine Fluviral for the 2008-2009 season in adults over the age of 18.

NCT ID: NCT00586469 Completed - Influenza Vaccines Clinical Trials

A Randomized Study to Compare the Safety and Immunogenicity of Fluviral® Made With New Versus Aged Bulk

Start date: December 14, 2007
Phase: Phase 4
Study type: Interventional

Vaccination is currently the most effective means of controlling influenza and preventing its complications and mortality in persons at risk. Once a year, a meeting of World Health Organization (WHO) experts takes place, leading to a recommendation on the influenza A and B strains that should be used for the production of vaccine for the coming influenza season. For the strains which do not change from the previous year, the vaccine can be formulated from the old mono bulk from the previous year. Bulks as old as 12 months may be blended to make trivalent inactivated vaccine (TIV) under the current Canadian and US licenses. This study is conducted to evaluate safety and immunogenicity of Fluviral vaccines made with the aged bulk material compared with the new bulk material. This protocol posting has been updated in order to comply with the FDA Amendment Act, Sept 2007.

NCT ID: NCT00449670 Completed - Influenza Clinical Trials

Assess Consistency of Immunogenicity of GlaxoSmithKline Biologicals' Pandemic Influenza Vaccine (GSK1562902A) in Adults

Start date: March 24, 2007
Phase: Phase 3
Study type: Interventional

The present study is designed to assess the lot-to-lot consistency of the immunogenicity of a GlaxoSmithKline Biologicals' pandemic influenza candidate vaccine (GSK1562902A) in adults aged between 18 and 60 years.

NCT ID: NCT00430521 Completed - Influenza Clinical Trials

Safety & Immunogenicity of an Alternative Immunization Schedule of GSK Bio's Pandemic Influenza Vaccine (GSK1119711A)

Start date: February 5, 2007
Phase: Phase 2
Study type: Interventional

The aim of the study is to assess the safety & immunogenicity of a pandemic influenza vaccine administered at 2 different time points. The Protocol Posting has been updated in order to comply with the FDA Amendment Act, Sep 2007.

NCT ID: NCT00402805 Completed - Clinical trials for Lung Transplantation

Improving the Humoral Response to Influenza Vaccine in Lung Transplant Recipients by an Intradermal Strategy

Start date: October 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to test the specific humoral response after an intramuscular and intradermal influenza vaccination in lung transplant recipients

NCT ID: NCT00306995 Completed - Influenza Clinical Trials

Safety Study of Pandemic Candidate Influenza Vaccines in the Elderly Population

Start date: May 11, 2005
Phase: Phase 2
Study type: Interventional

Influenza pandemics are caused by viruses that possess an Hemagglutinin molecule to which most of the population lacks immunity. If such virus is pathogenic to human and demonstrates the ability to transmit from person to person, the result is a global outbreak of disease that affects a high percentage of individuals in a short period of time and is likely to cause substantially increased mortality and morbidity in all countries of the world. Recently, purely avian influenza viruses, including the H5N1, H9N2 and H7N7 subtypes, have been directly transmitted to humans, raising concern over the possibility of a new influenza pandemic among the world's immunologically naive populations. In order to face this kind of situation, a pandemic influenza vaccine has to be developed.

NCT ID: NCT00296270 Completed - Influenza Vaccines Clinical Trials

Memory for Flu Facts and Myths and Effects on Vaccine Intentions

Start date: March 2005
Phase: N/A
Study type: Interventional

Objectives: To determine whether people systematically misremember the “myths” (false information) as true, and to assess effects on perceptions of risk and behavioral intentions.

NCT ID: NCT00265161 Completed - Influenza Vaccines Clinical Trials

The Effectiveness of Influenza Vaccine Among Health Care Workers in a Hospital Setting.

Start date: December 2005
Phase: N/A
Study type: Observational

The study will be held in the winter of 2005-2007. The aim is to assess the effectiveness of the influenza vaccine in health care workers (HCW).