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Influenza, Human clinical trials

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NCT ID: NCT02072174 Completed - Clinical trials for Influenza and Acute Respiratory Viral Infections

Efficacy of Anaferon for Children in the Treatment of Influenza and Acute Respiratory Viral Infections in Children

Start date: October 8, 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is: • To obtain additional data on therapeutic efficacy of Anaferon for children in the treatment of influenza and acute respiratory viral infections in children

NCT ID: NCT02071914 Completed - Influenza A Clinical Trials

A Study to Evaluate the Efficacy and Safety of CT-P27 in an Influenza Challenge Model

Start date: February 15, 2014
Phase: Phase 2
Study type: Interventional

This study is to evaluate the efficacy of CT-P27 measured by quantitative PCR viral load from nasopharyngeal mucosa, compared to placebo.

NCT ID: NCT02071329 Completed - Influenza A Clinical Trials

Safety, Tolerability, Efficacy and Immunogenicity of an Influenza A Vaccine (FP-01.1) in Healthy Volunteers Following Virus Challenge

Start date: January 2014
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to assess the safety, tolerability, efficacy, and immunogenicity of an influenza A vaccine (vaccine: FP-01.1), as compared to placebo, in healthy volunteers following a dose of influenza A virus.

NCT ID: NCT02067286 Completed - Influenza A Clinical Trials

Detection of Influenza A, Influenza B, and RSV Using the Liat™ Assays on the Liat™ Analyzer

Start date: January 2014
Phase: N/A
Study type: Observational

The objective of this study is to evaluate the clinical sensitivity and specificity of the Liat™ Influenza A/B & RSV Assay and the Liat™ Influenza A/B Assay when used on the Liat Analyzer to detect the presence or absence of Influenza A, Influenza B, and RSV in a nasopharyngeal swab specimen as compared to an FDA approved NAAT and culture.

NCT ID: NCT02062281 Completed - Influenza Clinical Trials

Study of Evaluating Safety and Immunogenicity of 23-Valent Pneumococcal Polysaccharide Vaccine With Influenza Vaccine in Children and Adults

Start date: November 2013
Phase: Phase 4
Study type: Interventional

The 23-valent pneumococcal Polysaccharide vaccine (23vPPV) has been developed for children and adults to prevent pneumococcal diseases such as pneumonia (inflammation of the lungs), meningitis (inflammation of the brain lining), and septicemia (blood poisoning) since 2006 in China. Also, the trivalent influenza vaccine (TIV) is frequently administered to the children and adults. The main objective of this study is to show that both vaccines can safely be administered together without affecting the immune response of protecting against disease.

NCT ID: NCT02056340 Completed - Influenza Clinical Trials

Statin Therapy in Acute Influenza

Start date: October 2013
Phase: Phase 2
Study type: Interventional

Influenza (the 'flu') is a common virus infecting approximately 5-20% of the population in the United States and causing as many as 500,000 deaths worldwide each year. Currently, there are only a few treatments for influenza infection and none of these target inflammation that can be caused by the virus. This study will test whether the anti-inflammatory effects of statins, a class of drugs most often used to treat high cholesterol, will decrease the severity of illness in patients who are infected with influenza by testing markers of inflammation in the blood and recording resolution of influenza illness.

NCT ID: NCT02045472 Completed - Influenza Clinical Trials

A Study of VIS410 to Assess Safety and Pharmacokinetics

Start date: September 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety, tolerability, immunogenicity and pharmacokinetics of single escalating doses of VIS410 in healthy volunteers.

NCT ID: NCT02035696 Completed - Influenza Clinical Trials

Safety and Immunogenicity of a Four Influenza Vaccines in Children Ages 6 Months Old to Less Than 48 Months Old

Start date: December 2013
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the safety and immunogenicity of four influenza vaccines in children 6 months to < 48 months of age

NCT ID: NCT02027233 Completed - Clinical trials for Severe Acute Respiratory Infection

Clinical Trial to Assess the Influenza Vaccination of the Hospitalized Adults

FLUVAC EV-03
Start date: January 2014
Phase: N/A
Study type: Interventional

This study assesses the seasonal of influenza vaccine effectiveness in adults hospitalised with laboratory-confirmed influenza through a network of hospitals in France. Also, To better understand the burden of other respiratory viruses such as respiratory syncytial virus (RSV) and SARS-CoV-2 in hospitalized adults, we need to describe and quantify the population hospitalized due to theses other respiratory viruses.

NCT ID: NCT02026349 Completed - Influenza Clinical Trials

Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316

Start date: January 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if favipiravir is effective in reducing the time to resolution of influenza symptoms.