Low-dose Interleukin-2 in Combination With Standard Therapy on Idiopathic Inflammatory Myopathy

Inflammatory Myopathy Clinical Trial

Official title:
A Randomized Controlled Trial to Evaluate the Efficacy and Safety of Low-dose Interleukin-2 in Combination With Standard Therapy Compared to Standard Therapy Alone in Adults With Active Idiopathic Inflammatory Myopathy

Status Not yet recruiting

Clinical Trial Summary

This study aims to explore the clinical and immunological efficacy of low-dose Interleukin-2 (IL-2) and cyclosporin a (CSA) on idiopathic inflammatory myopathy (IIM)

Clinical Trial Description

The investigators designed a radomized control study. Adults with active IIM will be enrolled. IIM is defined as Dermatomyositis (DM) or Polymyositis (PM), meeting the Bohan & Peter (1975) diagnostic criteria for definite or probable DM or PM. Patients will be randomly divided into 2 groups arranged by registration order. One million units of Recombinant Human Interleukin-2 (rhIL-2) was administered subcutaneously every other day for 3 months. All patients were followed up for 3 months after withdraw of IL-2. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04237987
Study type	Interventional
Source	Peking University People's Hospital
Contact	MIAO MIAO
Phone	8618810024336
Email	miao18734897489@126.com
Status	Not yet recruiting
Phase	Phase 2
Start date	January 21, 2020
Completion date	April 8, 2021

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