Pentoxifylline as Adjunctive Therapy in Patients With Ulcerative Colitis

Status Recruiting

Clinical Trial Summary

The exact underlying mechanisms of ulcerative colitis (UC), an idiopathic, chronic inflammatory disease marked by diffused inflammation of the colon and rectum mucosa, are still unknown. Due to genetic, immune, and environmental factors, UC is highly dependent on cellular immune reactions and exaggerated inflammatory responses. The release of several cytokines, kinins, leukotrienes, platelet-activating factor (PAF), and reactive oxygen species is connected to immunological activity (ROS). Additionally, many of the cytokines will start an acute phase response, making the inflammation worse.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05558761
Study type	Interventional
Source	Tanta University
Contact	Mostafa M Bahaa, PhD
Phone	0201025538337
Email	mbahaa@horus.edu.eg
Status	Recruiting
Phase	Phase 2
Start date	October 10, 2022
Completion date	February 20, 2025

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