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Clinico-biological Collection to Investigate the Physiopathology of Systemic Autoimmune Diseases — ESSAi  

Inflammatory Bowel Diseases Clinical Trial

Official title:
Constitution of a Collection of Biological Samples With the Aim of Carrying Out Clinico-biological and Pathophysiological Investigations of Systemic Autoimmune Diseases

Clinical Trial Summary

The aim of this project is to start a biological and clinical collection of patients presenting systemic autoimmune disease. This collection will provide appropriate biological samples to identify new biomarkers and to be accessible to the medical, scientific and industrial communities for the identification of new therapeutic strategies

Clinical Trial Description

Autoimmune diseases group together less than a hundred different clinical entities which are for the most part rare pathologies but which, in combination, concern 5-8% of the adult population with a strong female predominance (FAI²R: the disease chain rare autoimmune and auto-inflammatory drugs, fai2r.org). The common denominator of all these diseases is based on the breakdown of self-tolerance which is the origin of self-reactivity and whose physiopathological mechanisms are still not fully understood, which generates numerous cross-sectional or fundamental studies. In addition to this complexity, there are significant inter-individual variabilities which lead to the definition of subgroups of patients on the basis of the clinical-biological profile and / or the response to treatments. Consequently and in view of the need to establish the diagnosis early and then to propose the best treatment in the perspective of an individualized medicine, the clinical, biological and genetic characteristics of these subgroups of patients must be explored in order to improve diagnostic and therapeutic capacities. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05251415
Study type Observational
Source University Hospital, Toulouse
Contact Chloé BOST, MD, PhD
Phone 5 61 77 61 44
Email bost.c@chu-toulouse.fr
Status Recruiting
Phase
Start date April 4, 2022
Completion date April 4, 2032
View Details
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