Inflammatory Bowel Diseases Clinical Trial
Official title:
Serum NGAL as a Predictor of Clinical and Endoscopic Activity of Inflammatory Bowel Disease
Ulcerative colitis (UC) and Crohns disease (CD) represent the two major forms of inflammatory bowel disease (IBD), characterized by epithelial cell damage and prominent mucosal infiltration by inflammatory cells including granulocytes, macrophages, lymphocytes, and plasma cells.
Status | Not yet recruiting |
Enrollment | 80 |
Est. completion date | November 30, 2022 |
Est. primary completion date | November 29, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 15 Years and older |
Eligibility | Inclusion Criteria: IBD patients diagnosed by endoscopy. Male and female gender. Disease activity proven clinically and endoscopy . Assiut university hospital patients Exclusion Criteria: - Patients who refuse to contribute in this study Pregnancy and breast feeding Cancer patients Renal pathology Diabetes Mellitus Cardiovascular patients Pancreatitis COPD patients |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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Assiut University |
Nakov R. New markers in ulcerative colitis. Clin Chim Acta. 2019 Oct;497:141-146. doi: 10.1016/j.cca.2019.07.033. Epub 2019 Jul 27. Review. — View Citation
Oikonomou KA, Kapsoritakis AN, Theodoridou C, Karangelis D, Germenis A, Stefanidis I, Potamianos SP. Neutrophil gelatinase-associated lipocalin (NGAL) in inflammatory bowel disease: association with pathophysiology of inflammation, established markers, and disease activity. J Gastroenterol. 2012 May;47(5):519-30. doi: 10.1007/s00535-011-0516-5. Epub 2011 Dec 27. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | test the sensitivity and specificity of using NGAL in diagnosis of IBD | test the sensitivity and specificity of using NGAL in diagnosis of IBD | One year |
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