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Clinical Trial Summary

RCT to evaluate possible pharmacokinetic differences between the two current regimes of intensified adalimumab administration.


Clinical Trial Description

IBD patients in need of intensified adalimumab treatment will be randomized to receive 40mg sc weekly or 80mg sc every two weeks, and after 6 weeks of treatment each of the groups will be allocated to the other dosing regime. Adalimumab blood levels and other features such as specific drug antibodies and disease activity parameters will be compared between both groups. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04404517
Study type Interventional
Source Hospital Universitario La Paz
Contact Eduardo Martin Arranz, PhD
Phone +34912071350
Email emarranz@salud.madrid.org
Status Recruiting
Phase Phase 3
Start date October 1, 2019
Completion date October 30, 2021

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