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Correlation of Serum Adalimumab Levels at an Administration of 40 mg Weekly vs 80 mg Every Two Weeks — IntnsificADA  

Inflammatory Bowel Diseases Clinical Trial

Official title:
Correlation of Serum Adalimumab Levels at an Administration of 40 mg Weekly vs 80 mg Every Two Weeks

Clinical Trial Summary

RCT to evaluate possible pharmacokinetic differences between the two current regimes of intensified adalimumab administration.

Clinical Trial Description

IBD patients in need of intensified adalimumab treatment will be randomized to receive 40mg sc weekly or 80mg sc every two weeks, and after 6 weeks of treatment each of the groups will be allocated to the other dosing regime. Adalimumab blood levels and other features such as specific drug antibodies and disease activity parameters will be compared between both groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04404517
Study type Interventional
Source Hospital Universitario La Paz
Contact Eduardo Martin Arranz, PhD
Phone +34912071350
Email emarranz@salud.madrid.org
Status Recruiting
Phase Phase 3
Start date October 1, 2019
Completion date October 30, 2021
View Details
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