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Telomere Length and Other Parameters of Telomere Dysfunction in PSC and Colitis

Inflammatory Bowel Disease Clinical Trial

Official title:
Primary Sclerosing Cholangitis Telomere Length

Clinical Trial Summary

PSC is a chronic cholestatic disorder. The investigators intend to study some telomere parameters and telomere length in order to predict a premalignant state.

Clinical Trial Description

Primary sclerosing cholangitis (PSC) and colitis are chronic inflammatory disorders with malignant potential. Telomerase is an enzyme complex that lengthens telomeres and has enhanced expression in numerous malignancies. In this study, we evaluated the telomerase gene copy number, telomere length, cells in senescence, aneuploidy and additional parameters of telomere dysfunction from peripheral blood lymphocytes of patients. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02247622
Study type Observational
Source Meir Medical Center
Contact Ido Laish, MD
Phone +972-549477261
Email ido.laish@gmail.com
Status Recruiting
Phase N/A
Start date February 2012
Completion date September 2014
View Details
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