Clinical Trials Logo

Clinical Trial Summary

The objective of this observatory is to provide a national database of infective endocarditis, informed by all volunteer centers, using a standardized case report forms. Such an observatory will describe the clinical profile, microbiological, therapeutic and evolving of infective endocarditis (IE); analyze the risk factors for the disease and its prognosis factors of evolution; describe management practices; evaluate and compare in the real drug treatment strategies (including antibiotics) and surgical.


Clinical Trial Description

All the clinical, biological, microbiological and laboratory describing the history of patients and their evolution during hospitalization for infective endocarditis will be obtained from physicians supporting patients and recorded in an electronic case report form. Will include collected clinical characteristics (site, pre-existing heart disease underlying symptoms, complications), biological characteristics (dosage on admission and diagnosis), microbiological characteristics (identifying the genus and species of the microorganism responsible, sensitivity to antibiotics susceptibility testing and evaluated by determination of minimal inhibiting concentration (MIC), exhaustive search of the rare forms of endocarditis uncultivated microorganisms), an analysis of the gateways based on the causative organism; echocardiographic characteristics (number and size of vegetations, valvular damage, scalable: surgery, lethality) and therapeutic characteristics (antibiotic treatment, surgical). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03272724
Study type Observational
Source Central Hospital, Nancy, France
Contact Nadine JUGE, PhD
Email n.juge@chru-nancy.fr
Status Recruiting
Phase
Start date January 1, 1991
Completion date December 31, 2025

See also
  Status Clinical Trial Phase
Recruiting NCT05862025 - Evaluation of the Usefulness of Echocardiography in Patients With Staphylococcus Aureus Bacteremia (ET-AUREUS Study). N/A
Completed NCT03590106 - Cardiac Surgery Peer Recovery Support Program N/A
Not yet recruiting NCT05563662 - SURgical Registry of ENDocarditis EuRope
Completed NCT00947817 - Impact of Endothelial Cell Activation and Modifications of Haemostasis Induced by Infective Endocarditis on the Risk of Embolism N/A
Recruiting NCT00624091 - Rationale, Design and Methods for the Early Surgery in Infective Endocarditis Study (ENDOVAL) Phase 4
Terminated NCT00695903 - Phase 2 Study of Safety, Efficacy, and Pharmacokinetics of Higher Doses of Daptomycin and Vancomycin in MRSA Bacteremia Phase 2
Recruiting NCT04992923 - Prospective Cohort Study of Patients With Infective Endocarditis at Pitié-Salpêtrière Hospital
Recruiting NCT03642379 - Cardiac Surgery Peer Support Recovery N/A
Recruiting NCT05264181 - Transcatheter Pulmonary Valve Implantation With SAPIEN 3 Valve
Recruiting NCT04257292 - NExt-Generation Sequencing and Cell Culture-based Characterization of S. Aureus in Infective Endocarditis
Active, not recruiting NCT03683355 - Characterization of RadiOlabeled Tracer Uptake Pattern in Noninfected Transcatheter Aortic Valves.
Not yet recruiting NCT00562653 - Autoantibodies and Clinical Symptoms in Infective Endocarditis Patients N/A
Not yet recruiting NCT00550823 - Cardiac Computarized Tomography in Infective Endocarditis N/A
Completed NCT03153384 - Impact of the Blood Culture Technique on the Diagnosis of Infective Endocarditis
Not yet recruiting NCT06194409 - The Incidence, Clinical Characteristics and Outcome of Infective Endocarditis Among Intravenous Drug Abusers Versus Non-Drug Abusers.
Completed NCT03945708 - Does Whole Blood Adsorber During CPB Reduce Vasoactive Drugs Postoperatively in Endocarditis Patients Undergoing Valve Surgery? N/A
Not yet recruiting NCT06269679 - CBCT vs OPT on the Oral Health Status at 12 Months of Patients Hospitalized for Infective Endocarditis. N/A
Recruiting NCT03626571 - PET/MR Imaging In Patients With Infective Endocarditis
Completed NCT03612245 - Hygiene and Bucco-dental Status of Patients With Oral Streptococcal Endocarditis
Completed NCT02910856 - Infective Endocarditis in the Elderly