Quantification of Transition Metals

Infections Clinical Trial

Official title:

Quantification of Transition Metals in Patients at the Cologne University Hospital

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT02222779
• Other study ID #: KPUK-14-Metal
• Status: Not yet recruiting
• Phase: N/A
• First received: August 20, 2014
• Last updated: August 20, 2014
• Start date: September 2014

Study information

• Verified date: August 2014
• Source: University of Cologne
• Contact: Uwe Fuhr, Professor
• Phone: 0049221478
• Email: uwe.fuhr[@]uk-koeln.de
• Is FDA regulated: No
• Health authority: Germany: no higher federal authority needed due to being a non-interventional study
• Study type: Observational

Clinical Trial Summary

In this trial, concentrations of transition metals of interest are quantified in surplus cerebrospinal fluid (CSF) and blood serum samples. Quantification of the transition metals will be performed by inductively coupled plasma mass spectrometry (ICP-MS). The treating physicians as well as the patients will not be informed about the results of drug concentrations.

Description:

Samples used include:

Remaining portions of samples collected for diagnostic or therapeutic reasons (paired CSF and blood serum samples). No lumbar puncture will be done specifically for this protocol.

The objective of this study is to gain an overview about transition metals concentrations in blood serum and CSF in order to provide preliminary data on patients. The effect of neurodegenerative diseases on metals or the other way round will be assessed if possible.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 3000
• Est. primary completion date: August 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria: •

• The trial will include any patient (with various diseases, especially neurodegenerative diseases) who received a lumbar puncture.

Exclusion Criteria:

• • The lower age limit is 18 years. In concordance with the objective of the project there is no specific exclusion criteria.

Study Design

Observational Model: Ecologic or Community

Related Conditions & MeSH terms

• Infections
• Neurodegenerative Diseases

Locations

Country	Name	City	State
Germany	Department of Pharmacology	Cologne	Northrhine Westphalia

Sponsors (1)

Lead Sponsor	Collaborator
University of Cologne

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Transition metal concentration		5 years