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Ertapenem for Initial Empirical Treatment of Third Generation Cephalosporin Resistant Enterobacteriaceae Bacteremia

Bacteremia Clinical Trial

Official title:
Ertapenem for Initial Empirical Treatment of Third Generation Cephalosporin Resistant Enterobacteriaceae Bacteremia: a Propensity Score Analysis

Clinical Trial Summary

This study aims to assess whether ertapenem as an empiric treatment of third-generation-cephalosporin resistant Enterobacteriaceae (3GCRE) bacteremia is non-inferior to other carbapenems in term of 30-day mortality.

Clinical Trial Description

There are limited data of the efficacy of ertapenem as the empiric treatment of serious invasive infections, such as bloodstream infections (BSIs), that are due to ESBL-producing Enterobacteriaceae. Previous studies of ertapenem were done in small group of patients, in less invasive infection, as a definite 'step-down' therapy, or as compared to other non-carbapenem antibiotics. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03925402
Study type Observational
Source Phramongkutklao College of Medicine and Hospital
Contact
Status Completed
Phase
Start date May 15, 2019
Completion date October 1, 2022
View Details
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