Infant, Premature Clinical Trial
Official title:
Less Invasive Beractant Administration in Preterm Infants: a Pilot Study.
The aim of this study is to assess the efficacy and feasibility of a new less invasive surfactant administration (LISA) technique with a specific designed cannula for surfactant administration using Beractant replacement in preterm infants <32 weeks of gestation and compare short and long term outcomes with the intubation, administration of surfactant and extubation method (INSURE). This was a single-center, prospective, open-label, non-randomized, controlled study with an experimental cohort of 30 patients treated with LISA and a retrospective control group comprising the 30 most recently treated patients with INSURE. Beractant (4 ml/Kg) was administered as exogenous surfactant in both groups if patients on nasal continuous positive airway pressure (nCPAP) during the first three days of life were needed of more than 30% of fraction of inspired oxygen inspired oxygen fraction (FiO2).
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03146351 -
The Effects of Family Centered Intervention Program on Preterm Infants
|
N/A | |
Completed |
NCT02064712 -
Determining an Optimal Weaning Method of Nasal Continuous Positive Airway Pressure in Preterm Neonates
|
N/A | |
Completed |
NCT00365703 -
Nasogastric Tube vs. Orogastric Feeding Tube in Preterm Infants: Which is Best?
|
N/A | |
Terminated |
NCT00179933 -
The Impact of Implementing NIDCAP on Preterm Infants in the NICU
|
N/A | |
Completed |
NCT00114543 -
Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight
|
Phase 3 | |
Terminated |
NCT05030012 -
Maintaining Optimal HVNI Delivery Using Automatic Titration of Oxygen in Preterm Infants
|
N/A | |
Completed |
NCT00552383 -
The Edmonton Randomised Controlled Trial of NIDCAP - Based Developmental Care
|
N/A | |
Completed |
NCT00011362 -
Dexamethasone Therapy in VLBW Infants at Risk of CLD
|
Phase 3 | |
Completed |
NCT06308471 -
Effect of Baby Massage on Oral Motor Skills of Premature Babies
|
N/A | |
Completed |
NCT01863043 -
Aspiration of Residual Gastric Contents
|
N/A | |
Completed |
NCT05462509 -
Feasibility of Use of the PATH bCPAP and Oxygen Blenders Device With Neonates in Uganda
|
N/A | |
Not yet recruiting |
NCT06109350 -
The Effect of Physical Therapy Intervention on Motor Performance in Bhutanese Preterm Infants
|
N/A | |
Completed |
NCT03551600 -
Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus
|
||
Terminated |
NCT02599545 -
Testosterone and Cortisol Levels in Infants
|
||
Completed |
NCT01193270 -
Vitamin E for Extremely Preterm Infants
|
Phase 1 | |
Withdrawn |
NCT00536445 -
Use of NAVA in Intubated Preterm
|
Phase 1/Phase 2 | |
Completed |
NCT00455169 -
Influenza Vaccine in Premature Infants
|
Phase 4 | |
Completed |
NCT00579553 -
Comparing IM vs. Vaginal Progesterone for Pre-term Birth
|
N/A | |
Completed |
NCT01203423 -
Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study
|
||
Active, not recruiting |
NCT02863978 -
Preliminary Study to the Conception of a Non-invasive Neonatal Monitoring System With Development of a Database
|
N/A |