Infant, Premature Clinical Trial
Official title:
Nasogastric Tube vs. Orogastric Feeding Tube in Preterm Infants: Which is Best?
The purpose of this study is to find out which method (nasogastric vs. orogastric) of feeding tube for premature infants results in earlier only oral feeding.
Preterm infants, even as young as 23 weeks gestational age, can be fed enterally at the
first week of life. Coordination of sucking and swallowing, and coordination of both and
breathing is necessary for efficient and safe oral feeding, and is not well established
before the 35th week gestational age. That is why tube feeding is essential for preterm
infants younger than that age.
There is no consensus regarding the best way for the feeding tube, i.e. oral vs. nasal, and
whether placing the tube should be continuous or intermittently. Nasogastric tube has been
associated with vagal responses. Both tubes may cause gastric perforation.
Development and function of oral feeding has been described. It is known that non-nutritive
sucking and early introduction of oral feeding accelerate the transition from tube feeding
to oral feeding. It is suggested that the preterm infant may experience a maturational lag
in vagal function related to ingestive needs, which may contribute to continued feeding
difficulties and may be a measurable marker of subtle neurodevelopmental problems. Both oral
and nasal feeding tube may interfere with establishment of efficient oral feeding. The
purpose of this study is to see whether there is a difference between oral and nasal tube
feeding, regarding the institution of oral feeding.
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label
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