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Serum Vascular Endothelial Growth Factor in Infants With Intravitreal Ranibizumab

Infant, Premature, Diseases Clinical Trial

Official title:
Serum Concentrations of Vascular Endothelial Growth Factor in Infants Treated With Ranibizumab for Retinopathy of Prematurity

Clinical Trial Summary

To determine the serum concentrations of ranibizumab and vascular endothelial growth factor (VEGF) in infants with retinopathy of prematurity (ROP) who received intravitreal ranibizumab

Clinical Trial Description

Infants with ROP are studied. They received 0.25 mg or 0.5 mg of intravitreal ranibizumab to either 1 eye (unilateral cases) or both eyes (bilateral cases) with vascularly active ROP. Serum samples are collected 1 day before and 1 day, 3 days, 1 week after intravitreal ranibizumab. The serum concentrations of ranibizumab and VEGF are measured by enzyme-linked immunosorbent assay, and the changes of the serum VEGF levels are determined. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03115255
Study type Interventional
Source Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Contact
Status Completed
Phase N/A
Start date May 1, 2017
Completion date June 30, 2018
View Details
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