Using Isosorbide Mononitrate in Reducing Time in Induction of Labor in Post Date Women

Induction of Labor Clinical Trial

Official title:

Efficacy of Intravaginal Administration of Isosorbide Mononitrate Together With Misoprostol Versus Misoprostol Alone in Induction of Labor in Postdate Women

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03854383
• Other study ID #: 600181
• Status: Recruiting
• Phase: Phase 2
• Start date: March 3, 2019
• Est. completion date: July 1, 2019

Study information

• Verified date: March 2019
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

We will compare between using isosorbide mononitrate together with misoprostol versus the misoprostol alone in induction of labor in postdate women

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: July 1, 2019
• Est. primary completion date: May 1, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 20 Years to 35 Years

Eligibility

Inclusion Criteria:

• age (20-35 yrs)

• single fetus

• gestational age > 40weeks

• not in labor

• bishop score < 7

• no medical disorder

Exclusion Criteria:

• Gestational age =40 weeks

• patient with a ripe cervix

• rupture of membranes

• suspected chorioamnionitis

• placenta previa

• history of major uterine surgery

• hypertonic uterine pattern

• contraindicated to receive PG

• fetal malpresentation

• multiple pregnancy

• intrauterine growth retardation

• women with any general medical disorder

Related Conditions & MeSH terms

• Induction of Labor

Intervention

Drug:
• Isosorbide mononitrate
Administration of isosorbide mononitrate vaginaly together with misoprostol in induction of labor in postdate women
• Misoprostol
Used intravaginally to ripe the cevix in induction of labor

Locations

Country	Name	City	State
Egypt	Ain Shams maternity hospital	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Abdelrahman Ali Fadel Youssef Mohamed

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The duration of induction to active phase interval	Measure the time between the beginning of the induction to enter the active phase of labor	12 weeks