Cervical Foley Plus Vaginal Misoprostol for Labor Induction

Status Completed

Clinical Trial Summary

The purpose of this study is to compare the efficacy of the combination of the supracervical foley bulb and vaginal misoprostol to vaginal misoprostol alone for labor induction. We hypothesize that use of the foley bulb plus vaginal misoprostol will result in shorter induction to delivery time.

Clinical Trial Description

More than 22% of all gravid women undergo induction of labor in the United States for various indications. Although there are several techniques and methods for induction of labor, the best agent and method still remains uncertain. To date, there has been no randomized trial comparing foley bulb plus vaginal misoprostol versus vaginal misoprostol alone. The combination of a mechanical device (foley bulb) and synthetic prostaglandin may have an additive or synergistic effect, resulting in greater degree of cervical ripening and shorter induction to delivery time (IDT). The addition of a synthetic prostaglandin to the foley bulb may also overcome the frequent observation of cervical dilation to 4cm by the foley bulb without effacement. ;

Study Design

Related Conditions & MeSH terms

Induction of Labor

Clinical Trial Details

NCT number	NCT01279343
Study type	Interventional
Source	Washington University School of Medicine
Contact
Status	Completed
Phase	N/A
Start date	January 2011
Completion date	March 2014

View Details

See also
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Recruiting	`NCT03854383` - Using Isosorbide Mononitrate in Reducing Time in Induction of Labor in Post Date Women	Phase 2
Completed	`NCT01428037` - Safety and Efficacy Study of Vaginal Misoprostol for Cervical Ripening and Induction of Labor	Phase 3
Terminated	`NCT03752073` - Comparison of Two Mechanical Methods of Outpatient Ripening of the Cervix	N/A
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