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Induction Toripalimab and Chemotherapy in Locally Advanced Cervical Cancer

Cervical Cancer Clinical Trial

Official title:
Induction Toripalimab and Chemotherapy in Locally Advanced Cervical Cancer Patients With High Risk of Recurrence: A Prospective, Single-Arm, Phase II Trial

Clinical Trial Summary

To explore the efficacy of incorporating neoadjuvant immunotherapy into neoadjuvant chemotherapy in locally advanced cervical cancer patients with high risk of recurrence.

Clinical Trial Description

For locally advanced cervical cancer patients undergoing definitive chemoradiotherapy, distant metastasis has become a major concern. In this study, investigators selected a subgroup of patients with theoretically higher risk of distant metastasis and intensified their systematic treatment by incorporating PD-L1 inhibitors into neoadjuvant chemotherapy, in order to reduce their risk of distant metastasis and achieve good disease-free survival. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06093438
Study type Interventional
Source Tianjin Medical University Cancer Institute and Hospital
Contact Yuanjie Cao
Phone +86-18522123151
Email cyjro325@gmail.com
Status Recruiting
Phase Phase 1/Phase 2
Start date July 1, 2023
Completion date July 1, 2026
View Details
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