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Clinical Trial Summary

The purpose of this study is to evaluate the efficacy and safety of decitabine combined with HAAG regimen in the treatment of newly diagnosed patients with ETP-ALL/LBL, T/M-MPAL and ALL/LBL with myeloid or stem cell markers.


Clinical Trial Description

This is a phase 3, open label, single arm, multi-center study in newly diagnosed ETP-ALL/LBL, T/M-MPAL and ALL/LBL patients who have myeloid or stem cell markers. The patients will receive decitabine combined with HAAG regimen in the induction treatment. The patients who respond to induction chemotherapy will undergo consolidation chemotherapy, and an optional allogeneic hematopoietic stem cell transplantation and post-transplantation maintenance treatment with decitabine according to patient's wishes. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04446130
Study type Interventional
Source The First Affiliated Hospital of Soochow University
Contact Xiaowen Tang, Ph.D.
Phone (0086)51267781856
Email xwtang1020@163.com
Status Recruiting
Phase Phase 3
Start date January 1, 2019
Completion date January 1, 2024

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