Effects of Mineralocorticoid Receptor Stimulation on Cognition

Individuality Clinical Trial

— MR-STIM  

Official title:

Effekte Von Fludrocortison Auf Soziale Kognition Und Gedächtnis Unter Berücksichtigung Von Geschlechtereffekten

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02478034
• Other study ID #: WI-CO-2
• Status: Completed
• Phase: N/A
• First received: June 11, 2015
• Last updated: March 4, 2016
• Start date: May 2015
• Est. completion date: March 2016

Study information

• Verified date: March 2016
• Source: Charite University, Berlin, Germany
• Contact: n/a
• Is FDA regulated: No
• Health authority: Germany: Ethics Commission
• Study type: Interventional

Clinical Trial Summary

In this study the effects of mineralocorticoid stimulation on social cognition will be investigated in healthy young individuals.

Description:

80 healthy young individuals (40 females and 40 male) will be recruited an randomized to either placebo or 0.4 mg Fludrocortison before testing. Tasks will on emotion recognition, Task Switch, visual spacial memory and decision making will be conducted.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: March 2016
• Est. primary completion date: March 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• free of medication

• age 18 - 30

Exclusion Criteria:

• any medication

• severe illness

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Individuality

Intervention

Other:
• Fludrocortisone
effects of fludrocortisone on cognition compared to placebo

Locations

Country	Name	City	State
Germany	Charite University	Berlin

Sponsors (1)

Lead Sponsor	Collaborator
Charite University, Berlin, Germany

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	social cognition	computer based tests: emotion recognition	25 min	No
Secondary	memory	computer based test on visuospacial memory	20 min	No
Secondary	decision making	computer based tests: BART	25 min	No