Intraileal Glucose vs. Saline Infusion on Hormone Secretion and Glycemic Excursions

Incretins Clinical Trial

Official title:
Comparative Effects of Intraileal Glucose vs. Saline Infusion on Hormone Secretion and Glycemic Excursions in Subjects With Ileostomy

Status Completed

Clinical Trial Summary

The distal ileum, where the glucagon-like peptide 1 (GLP-1) releasing cells predominate, is an important organ in mediating glycemic control. However, the distal ileum is not easy to access and the correspond in vivo research remains to be difficult. The investigators intend to recruit subjects who underwent rectal surgery with simultaneous protective ileostomy and evaluate hormone secretion and glycemic excursions via ileostomy glucose or saline infusion, and quantify the glucose absorption rate within the distal ileum.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Incretins

Clinical Trial Details

NCT number	NCT05030376
Study type	Interventional
Source	Qilu Hospital of Shandong University
Contact
Status	Completed
Phase	N/A
Start date	September 22, 2021
Completion date	March 1, 2022

View Details

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