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Incisional Hernia clinical trials

View clinical trials related to Incisional Hernia.

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NCT ID: NCT00998907 Completed - Wound Infection Clinical Trials

PDS*Plus and Wound Infections After Laparotomy

PDS*plus
Start date: September 2009
Phase: N/A
Study type: Interventional

The aim of this study is to ascertain if the use of PDS plus® reduces the number of wound infections and incisional hernia after midline and transverse laparotomy comparing to polyglactin suture.

NCT ID: NCT00970515 Terminated - Incisional Hernia Clinical Trials

Laparoscopic or Conventional Mesh Repair of Incisional and Umbilical Hernia

EVENTRALAP
Start date: November 2009
Phase: N/A
Study type: Interventional

The aim of this study is to compare immediate and long-term (24 months) results of laparoscopic and open mesh repair of incisional and umbilical hernia.

NCT ID: NCT00907842 Completed - Incisional Hernia Clinical Trials

Hernia Prevention in Stomas

Start date: April 2010
Phase: N/A
Study type: Interventional

Knowing that the risk of stoma associated herniation (parastomal or incisional) is 30-50% and the associated morbidity significant, standard placement of a prophylactic mesh upon stoma creation might prevent parastomal (or incisional herniation, after closure) and improve the quality of life of a large group of patients. This study is meant to be a pilot study to see whether the mesh related risks of infection and adhesion morbidity are acceptable if the mesh is placed intraperitoneally.

NCT ID: NCT00891254 Completed - Incisional Hernia Clinical Trials

Long-term Follow-up of Incisional Hernia Repaired With Intraperitoneal Mesh

Start date: January 2009
Phase: Phase 1
Study type: Interventional

The intraperitoneal repair has been proven safe for the repair of incisional hernia and is accepted, together with the subfascial or retromuscular repair as the "gold-standard" for the repair of incisional hernia. However no studies have convincingly proven that this approach is better than the on-lay repair. The authors believe that the intraperitoneal repair performs better than the on-lay repair for incisional hernia.

NCT ID: NCT00775034 Completed - Incisional Hernia Clinical Trials

Drainage Versus Sealant in Double Blinded Monocentric Open Incisional Hernia Repair

DREAM
Start date: January 27, 2010
Phase: Phase 4
Study type: Interventional

Mesh repair for open incisional hernia repair with fibrin sealant or with drainage

NCT ID: NCT00761475 Completed - Clinical trials for Incisional Hernia Occurence

Primary Mesh Closure of Abdominal Midline Wounds

PRIMA
Start date: February 2009
Phase: Phase 3
Study type: Interventional

Incisional hernia is the most frequently seen long term complication in surgery causing much morbidity and even mortality in patients. Despite studies on the optimal closing technique for laparotomies, the risk for incisional hernia after midline incision remains about 5-20 %. Major risk factors for incisional hernia after a laparotomy, like obesity, steroid use, malnutrition, smoking and connective tissue disorders, are known. Despite this knowledge, there has not yet been developed a sufficient method for prevention. One specific group of high risk patients are patients with an abdominal aortic aneurysm (AAA). The relationship between aortic aneurysm and other abdominal wall hernias, like inguinal hernias, has been reported. Retrospective and prospective studies have shown an average risk for incisional hernia after AAA repair of 31.6 %. Another high risk group is the group of obese patients. Patients with a BMI of more than 27 have a high risk of developing an incisional hernia after midline incision with an incidence of 22% after 12 months. Considering only 50 % of incisional hernia will be clinically evident in the first 12 months, the total incidence will be above 30%. This high risk group of patients with obesitas and aneurysmatic disease can benefit most from prevention. Some small studies have been performed to evaluate the usefulness and safety of primary laparotomy wound closure with the aid of prosthetic mesh. These studies show a very low risk for incisional hernias and a low infection rate, even when used in contaminated wounds such as colostomal surgery. However, there has not been performed an adequate randomized controlled trial to study the prevention of incisional hernias. Our hypothesis is that incisional hernia prevention with use of prosthetic mesh after laparotomy is effective in patients with aortic aneurysm and in obese patients with a BMI of more than 27.

NCT ID: NCT00647569 Completed - Incisional Hernia Clinical Trials

Trial of Collagen Mesh for Prevention of Ventral Hernia After Surgery for Advanced Pelvic Cancer

VRAM
Start date: April 2008
Phase: Phase 3
Study type: Interventional

The aim of the present project is to investigate whether use of biological mesh at the donor site of the rotation flap in closure of the abdominal wall reduce the frequency of incisional hernia formation compared to the usual abdominal wall closure after abdominal rotation flap operation in surgery for advanced pelvic cancer.

NCT ID: NCT00537927 Completed - Ventral Hernia Clinical Trials

LACH-Trial: LAparoscopic Correction of Hernia

LACH
Start date: August 2005
Phase: N/A
Study type: Interventional

Method of fixation of the mesh in laparoscopic incisional / ventral hernia repair might influence the degree of postoperative pain. The study hypothesis is that there is no difference in postoperative pain between different methods to fix the mesh in laparoscopic incisional / ventral hernia repair.

NCT ID: NCT00508053 Completed - Wound Infection Clinical Trials

When Closing Midline Incisions, do Small Stitches Reduce the Risk for Incisional Hernia, Wound Infection or Dehiscence?

Start date: January 2001
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a technique using very small stitches when closing a midline incision can reduce the risk for wound complications such as incisional hernia, infection or dehiscence.

NCT ID: NCT00498810 Terminated - Incisional Hernia Clinical Trials

COMplete Versus PArtial Open inCisional Hernia Repair (COMPAC-TRIAL)

COMPAC
Start date: September 2007
Phase: N/A
Study type: Interventional

To compare the complete repair of the abdominal wall at the level of the former incision with only a partial repair at the level of the hernia in patients with an incisional hernia after median laparotomy in a prospective randomized trial.