Use of Acellular Dermal in the Incarcerated Inguinal Hernia Tension-free Reconstructions

Incarcerated Inguinal Hernia Clinical Trial

Official title: Use of Acellular Dermal in the Incarcerated Inguinal Hernia Tension-free Reconstructions

Status Active, not recruiting

Clinical Trial Summary

Incarcerated inguinal hernia is one of the common acute abdomen abdominal surgery, often prone to intestinal necrosis and acute peritonitis.Using traditional tension hernia reparation, the recurrence rate were as high as 30%. In recent years, biological materials especially acellular matrix materials (Acellular Dermal Matrix, ADM) in resisting the infection, has become a research hotspot. In the project, the investigators try to address the role of ADM in incarcerated inguinal hernia patients.

Clinical Trial Description

observation indicator:

1. recurrence rate after operation

2. incidence rate of complications

3. postoperative hospital stay

4. hospitalization costs

5. Self-evaluation of gastroesophageal reflux symptoms and quality of life(QOL) in 6th-month, 1st-year,2nd-year,3rd-year,4th-year and 5th-year after operation ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Hernia
• Hernia, Inguinal
• Incarcerated Inguinal Hernia

• NCT number: NCT02469142
• Study type: Interventional
• Source: Xijing Hospital of Digestive Diseases
• Status: Active, not recruiting
• Phase: Phase 2/Phase 3
• Start date: January 2015
• Completion date: December 2019