Ablation of Inappropriate Sinus Tachycardia — IST  

Inappropriate Sinus Tachycardia Clinical Trial

Official title: Ablation of Inappropriate Sinus Tachycardia Syndrome by Targeting Cardiac Neural Input

Status Terminated

Clinical Trial Summary

Hypothesis- Radiofrequency ablation, targeting the sympathetic input of the sinus node identified by 20Hz stimulation at the junction of the superior vena cava and the right atrium, will effectively reduce sinus rate acutely and will reduce palpitations due to inappropriate sinus tachycardia without the need for pacemaker implantation due to sinus node dysfunction post ablation.

Clinical Trial Description

Inappropriate sinus tachycardia syndrome describes a condition in which a patient's heart rate is intermittently (or persistently) higher than expected for the physiological circumstances, with ECG appearance indistinguishable from normal sinus rhythm, after the exclusion of medical conditions causing sinus tachycardia.

Hypothesis- Radiofrequency ablation, targeting the sympathetic input of the sinus node identified by 20Hz stimulation at the junction of the superior vena cava and the right atrium, will effectively reduce sinus rate acutely and will reduce palpitations due to inappropriate sinus tachycardia without the need for pacemaker implantation due to sinus node dysfunction post ablation. ;

Related Conditions & MeSH terms

• Inappropriate Sinus Tachycardia
• Tachycardia
• Tachycardia, Sinus

• NCT number: NCT00584649
• Study type: Interventional
• Source: University of Oklahoma
• Status: Terminated
• Phase: N/A
• Start date: April 2004
• Completion date: July 7, 2020