Psychiatric and Social Impacts of IVF

In Vitro Fertilization Clinical Trial

Official title:

Psychiatric and Social Impacts of In Vitro Fertilization.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05881044
• Other study ID #: Impacts of IVF
• Status: Not yet recruiting
• Start date: June 1, 2023
• Est. completion date: January 1, 2024

Study information

• Verified date: May 2023
• Source: Assiut University
• Contact: Marina Abdelmalak
• Phone: +2012184658331
• Email: marinaabdelmalak02[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To asses psychiatric impacts of In vitro fertilization.

Description:

Infertility and its treatment represent a global health area of increasing importance. Individuals experiencing infertility represent around 8-10% of couples worldwide. The demand for assisted reproduction techniques such as in-vitro fertilization (IVF) has increased in developed countries over the past decades, and is predicted to increase further in those to come . This could be further boosted by numbers in resource-limited settings of the developing world, where an estimated 180 million couples are experiencing infertility. The efficacy of IVF among the assisted fertility options has led an increasing number of individuals to seek this specific treatment. More than a half million babies are now born each year from IVF, as a result of over two million estimated annual treatment cycles . Yet it is also a relatively invasive and disruptive process that can be both physically and psychologically demanding . Infertility itself has been associated with a higher prevalence of depression and anxiety, lower quality of life, and lower self-esteem . The IVF process-which includes injectable medication and multiple blood tests, clinic appointments and procedures, waiting periods and anticipation of outcomes at each phase-may lead to further psychological stress. This can be exacerbated by disturbances to an individual's work and routine and the financial pressure of this costly treatment , and may be worse after multiple failed cycles .

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 52
• Est. completion date: January 1, 2024
• Est. primary completion date: September 1, 2023
• Gender: All
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• Couples who perform or planning or failed to perform in vitro fertilization.
• Age from 18y To 40y .

Exclusion Criteria:

• Couples with any Psychiatric disorders prior to marriage.
• Couples with any physical or mental handcapes.
• refusal of couples to give consent to join the study.

Related Conditions & MeSH terms

• In Vitro Fertilization

Intervention

Other:
• Psychiatric interview
Psychiatric interview which include personal identification, present history, past history and family history Complete physical and Neurological Examination. Mini Neuropsychiatric Interview scale. (MINI): to diagnosis psychiatric disorders Symptom checklist 90(SCL 90) Quality of life questionnaire. Hamilton Depression scale. Hamilton Anxiety scale. Socioeconomic scale (A.El.Gilany,A.El.Wehady,and M.EL.Wasify)

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (2)

Kocourkova J, Burcin B, Kucera T. Demographic relevancy of increased use of assisted reproduction in European countries. Reprod Health. 2014 May 26;11:37. doi: 10.1186/1742-4755-11-37. — View Citation

Mascarenhas MN, Flaxman SR, Boerma T, Vanderpoel S, Stevens GA. National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys. PLoS Med. 2012;9(12):e1001356. doi: 10.1371/journal.pmed.1001356. Epub 2012 Dec 18. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Measurement of depression in couples with IVF .	Measurement of psychiatric aspects in patients who perform or plan to perform in vitro fertilization by psychometric scales for measurement of depression such as The Hamilton Depression Rating Scale (HAM-D or HDRS) depression scale.; Scores below 7 generally represent the absence or remission of depression.; Scores between 7-17 represent mild depression; Scores between 18-24 represent moderate depression; Scores 25 and above represent severe depression	Baseline