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Immune Modulators and IVF

In Vitro Fertilization Clinical Trial

Official title:
Immune Modulators in Women Undergoing IVF----a Prospective Study

Clinical Trial Summary

Exploring the immune mediators of early pregnancy prospectively may help to identify new early interventions that will increase the likelihood of success and help women make informed decisions regarding their pregnancies.

Clinical Trial Description

Sera will be obtained from 500 women undergoing IVF at five time periods: cycle Day 2, post HCG, Day 24, Day 28, and/or Day 35.Aliquots of sera will be tested by commercial ELISA kits for concentrations of immune modulators suggestive to be predictive of IVF outcome, such as cytokines (interleukins, tumor necrosis factor, and interferon), neurotrophins (BDNF), protease inhibitors (HE4) and insulin-like growth factors (IGF-1, IGF-2, IGFBP). The results will be correlated with IVF outcomes. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02626702
Study type Observational
Source Weill Medical College of Cornell University
Contact
Status Terminated
Phase
Start date July 31, 2015
Completion date August 31, 2019
View Details
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