Impulsive Behavior Clinical Trial
— CDIC-tDCSOfficial title:
Measuring Cortical Dynamics of Inhibitory Control Before, During and After Transcranial Direct Current Stimulation (tDCS)
Verified date | February 2020 |
Source | Nottinghamshire Healthcare NHS Trust |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study aims to use concurrent Transcranial Direct Current Stimulation (tDCS) and Magnetoencephalography (MEG) with measures of impulsivity to examine the neurobiological underpinnings of rapid response impulsivity (RRI) and how these can be modified using tDCS in healthy subjects.
Status | Completed |
Enrollment | 36 |
Est. completion date | February 28, 2019 |
Est. primary completion date | February 14, 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 40 Years |
Eligibility |
Inclusion Criteria: - University students and staff - Aged 18-40 Exclusion Criteria: - Individuals with epilepsy and other neurological conditions, history of significant head injury, substance misuse, major mental disorder and those receiving psychotropic medication. - Contraindications to use of Magnetic Resonance (pacemakers, metal implants, aneurysm clips) - Pregnancy. |
Country | Name | City | State |
---|---|---|---|
United Kingdom | University of Nottingham | Nottingham | Notts |
Lead Sponsor | Collaborator |
---|---|
Najat Khalifa | Medical Research Council, University of Nottingham |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Alpha and Beta band activity | Evaluation of mechanism of action of tDCS using MEG data | During 20 minutes of tDCS stimulation | |
Primary | Total number of correct anti-saccade (AS) trials | A measure of rapid response impulsivity (inhibitory control) | Change from baseline after 20 minutes of tDCS | |
Secondary | Total number of correct pro-saccade (PS) trials | A behavioral measure of rapid response impulsivity (inhibitory control) | Change from baseline after 20 minutes of tDCS | |
Secondary | Saccade latency for anti-saccade (AS) trials | A behavioral measure of rapid response impulsivity (inhibitory control) | Change from baseline after 20 minutes of tDCS | |
Secondary | Saccade latency for pro-saccade (PS) trials | A behavioral measure of rapid response impulsivity (inhibitory control) | Change from baseline after 20 minutes of tDCS | |
Secondary | Total Scores on the UPPS+P Impulsive Behaviour Scale | A self-report measure of impulsivity | Baseline | |
Secondary | Alpha and Beta band activity | A Cortical measure of inhibitory control recorded using Magnetoencephalography (MEG). MEG is a brain imaging technique. | Change from baseline after 20 minutes of tDCS |
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