Clinical Trials Logo
  1. Home
  2. Implementation Science
  3. NCT06187662

BrighT STAR LIBRA: Leveraging Implementation Science for Blood Culture Reduction Approaches — LIBRA  

Implementation Science Clinical Trial

Official title:
BrighT STAR LIBRA: Leveraging Implementation Science for Blood Culture Reduction Approaches

Clinical Trial Summary

This study will compare two strategies that target distinct determinants of blood culture overuse in an exploratory, hybrid, pilot trial in 8 PICUs. It aims to determine if there is any association between specific strategies used to reduce blood culture overuse on unit-wide blood culture rates, patient safety, and concurrently explore aspects of the implementation process (acceptability, feasibility, appropriateness).

Clinical Trial Description

Blood cultures are an important test to diagnose bacterial bloodstream infections, but can be ordered reflexively, excessively, and lead to downstream negative patient consequences such as unnecessary antibiotic exposure. Work to date has demonstrated safe and effective reduction in blood culture rates in the pediatric intensive care unit (PICU) setting, but optimal strategies to reduce culture use are currently unknown. The primary study team will initially work with all enrolled sites in an identical fashion, facilitating a core series of steps for implementing a quality improvement blood culture diagnostic stewardship program which is identical to the steps used in the parent study, called BrighT STAR (Testing STewardship to reduce Antibiotic use and Resistance). In addition, the primary study team will randomize sites into two arms, in which different strategies are introduced that each target distinct determinants of blood culture overuse. The primary study team will examine the impact on blood culture rates, as well as evaluate aspects of the implementation process, in all sites pre- vs-post intervention. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06187662
Study type Interventional
Source Children's Hospital of Philadelphia
Contact
Status Enrolling by invitation
Phase N/A
Start date January 1, 2023
Completion date January 2025
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05586308 - Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation N/A
Recruiting NCT05050266 - Enhancing Mental and Physical Health of Women Veterans N/A
Not yet recruiting NCT06298253 - Behavioral Economics to Implement a Traffic Light Nutrition Ranking System: Study 2 N/A
Active, not recruiting NCT04710901 - uTECH: Machine Learning for HIV Prevention Among Substance Using GBMSM N/A
Not yet recruiting NCT05854212 - Behavioral Economics to Implement Nutrition Ranking in Food Pantries N/A
Active, not recruiting NCT04022850 - De-implementation of Low-value Pharmacological Prescriptions N/A
Not yet recruiting NCT06192511 - Implementing a Novel Consent Process for Biospecimen Research After Newborn Screening N/A
Enrolling by invitation NCT05344378 - Refining and Implementing Technology-Enhanced Family Navigation to Promote Early Access and Engagement With Mental Health Services for Youth With Autism N/A
Enrolling by invitation NCT05390411 - Seeking Objectivity in Allocation of Advanced Heart Failure (SOCIAL HF) Therapies Trial N/A
Recruiting NCT05172609 - An Exposure-Based Implementation Strategy to Decrease Clinician Anxiety Around Suicide Prevention N/A
Recruiting NCT05360849 - Implementing PrEP for Women Who Inject Drugs N/A
Not yet recruiting NCT05415891 - The IMPROV Project: Improving Mental Health and Substance Use Treatment Provision (IMPROV) Among People Living With HIV (Human Immunodeficiency Virus) in Atlanta N/A
Enrolling by invitation NCT04171830 - Clinical Surveillance Tool to Screen for Unmet Palliative Needs Among Patients in the Final Year of Life N/A
Enrolling by invitation NCT05374239 - Embedding the Fugl-Meyer Assessment in Occupational Therapists' Routine Practice N/A
Not yet recruiting NCT06375551 - K-ORCA: Testing a Decision Support Tool and Group Process for Selecting Interventions N/A
Completed NCT05240222 - Pre-Implementation Enhancement Strategy To Improve Teachers' Intention to Implement Evidence-Based Practices N/A
Not yet recruiting NCT06075108 - The P-KIDs CARE Health Systems Intervention in Tanzania N/A
Not yet recruiting NCT06215131 - Feasibility of Immersive Virtual Reality Dietician Program in Metabolic-dysfunction Associated Steatotic Liver Disease N/A
Withdrawn NCT04249141 - Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts
Recruiting NCT06180681 - Enhancing Team Effectiveness for a Collaborative School-based Intervention for ADHD N/A