Sperm DNA Fragmentation Effects on Blastocyst Morphology Grading, Pregnancy Rate and Implantation Rate

Blastocyst Clinical Trial

Official title:
The Correlation of Sperm DNA Fragmentation With Blastocyst Grading and Its Implantation Potential

Status Completed

Clinical Trial Summary

Retrospective cohort study for 189 couples assigned to normal and abnormal Sperm DNA fragmentation (SDF) groups.To determine the effect of SDF on blastocyst's trophectoderm (TE), Inner cell mass (ICM) morphology grading, and implantation rate. Semen in both groups was processed by density gradient (DG).

Clinical Trial Description

Purpose: to determine if sperm DNA fragmentation (SDF) has a correlation with Blastocyst's trophectoderm (TE) and Inner cell mass (ICM) grading, or with the implantation rate?

Method: Retrospective cohort study for 189 couples, assigned to normal SDF group (121 cases), and abnormal SDF group (68 cases). Semen in both groups was processed by double layer density gradient (DG).

Statistical analysis done using SPSS version 22. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04144621
Study type	Observational
Source	Ganin Fertility Center
Contact
Status	Completed
Phase
Start date	January 1, 2018
Completion date	April 1, 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02971878` - Comparisons of Human Embryonic Development Using Single Medium With and Without the Addition of Antioxidants	N/A
Recruiting	`NCT02575924` - Influence of Culture Media on Clinical Outcomes in Poor Responders or Severe Male Infertility	Phase 1
Completed	`NCT02999958` - Adding Antioxidants Into Human Sequential Culture Media System	N/A
Completed	`NCT05562479` - Effect of Sars-cov-2 on Donor Oocyte Quality and Quantity, a Multicenter Retrospective Study.
Completed	`NCT00521443` - Cryosurvival of Embryos From Dysmorphic Oocytes	N/A
Completed	`NCT00505115` - The Human Blastocyst Secretome and Implantome	N/A