Effects of ABO Blood Types on the Survival and Marginal Bone Resorption of Dental Implants

Implant Tissue Failure Clinical Trial

Official title:

Effects of ABO Blood Types on the Survival and Marginal Bone Resorption of Dental Implants

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04054271
• Other study ID #: 29112017/05
• Status: Completed
• Start date: December 15, 2017
• Est. completion date: December 15, 2018

Study information

• Verified date: August 2019
• Source: Yuzuncu Yil University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study evaluates implant survival and marginal bone resorption in patients receiving implant treatment with respect to demographic data and AB0 (groups) blood types.

Description:

For a successful dental implant, optimal soft and hard tissue characteristics are required. These characteristics include appropriate bone quality and a healthy adherent keratinized gingiva that surrounds the implant neck. The most common complications are peri-implant diseases and marginal bone loss for dental implants. Marginal bone loss around the implant may be observed as a long-term complication due to microbial dental plaque-induced peri-implant inflammatory disease or may be observed in the absence of such a disease.

The immune system and genetic factors are known to have important effects on implant success, and ABO blood types are also included in the genetic factors. In the studies evaluating the association of ABO blood types with increased susceptibility to infection and various systemic diseases, it was reported that the percentages of blood types differed significantly, especially in skeletal-muscle system injuries, fractures and cardiovascular disease susceptibility. Also some researchers reported that blood types may be effective on the bacteria colonization which is the main reason of the periodontal diseases. ABO blood types may have an impact on dental implant success and survival.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 963
• Est. completion date: December 15, 2018
• Est. primary completion date: December 15, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 19 Years to 78 Years

Eligibility

Inclusion Criteria:

• The inclusion criteria for the study group included being 18 years of age and non-smoker, not having any systemic disease, not having undergone any hard and soft tissue augmentation during implant surgery, having implants placed at bone level, having received cylindrical form implants with SLA surface structure, not missing any follow-up visits after implant surgery evidenced with radiographic recordings, having received flat abutment, having cemented implants, and being rehabilitated with fixed prosthetic restoration.

Exclusion Criteria:

• No

Related Conditions & MeSH terms

• Bone Resorption
• Implant Tissue Failure

Locations

Country	Name	City	State
Turkey	Serap Keskin Tunc	Van

Sponsors (1)

Lead Sponsor	Collaborator
Yuzuncu Yil University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Marginal bone resorption measurements (mm) in dental implants.	We evaluated marginal bone resorption in patients receiving implant treatment with respect to ABO blood types. These measurements will be measured by periapical radiographs. Periapical radiographs were taken with a parallel technique to measure the amount of mesial and distal bone resorption in the neck region of the implants.	1 year
Primary	Implant survival rates according to demographic data	We evaluated implant survival rates by age and sex on a yearly basis	1 year