Effect of Honey and Dexamethason on Extraction Healing

Impacted Third Molar Tooth Clinical Trial

Official title:

A Novel Therapeutic Approach for Controlling Complications Associated With Impacted Mandibular Third Molar Removal

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04848259
• Other study ID #: Impaction
• Status: Completed
• Phase: Early Phase 1
• Start date: January 5, 2021
• Est. completion date: June 27, 2021

Study information

• Verified date: July 2021
• Source: Al-Azhar University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Natural honey and dexamethason will be given before impaction removal then postoperative complications will be evaluated

Description:

Patient with impacted lower third molar will be selected to this study agording to agent applied preoperative. Group 1 will receive topical honey and Group 2 will receive IV dexamethason. After surgical removal of impacted tooth under local anesthesia postoperative pain mouth opening, and swelling will be evaluated

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: June 27, 2021
• Est. primary completion date: June 20, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• impacted 3rd molar

• healthy patient No smoking

Exclusion Criteria:

• history of smoking Medical disease

Related Conditions & MeSH terms

• Impacted Third Molar Tooth
• Tooth, Impacted

Intervention

Drug:
• Normal saline
Saline will be applied after surgery
• Dexamethasone
Dexamethason will be given IV before surgery
• Honey
Honey will be applied locally after surgery
• Dexamethasone and honey
Dexamethason will be given IV before surgery and then Honey will be applied locally after surgery

Locations

Country	Name	City	State
Saudi Arabia	Vision colleges	Jeddah

Sponsors (1)

Lead Sponsor	Collaborator
Al-Azhar University

Country where clinical trial is conducted

Saudi Arabia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Interincisal distance	Distance between upper and lower teeth will be measured in mm by ruler	Preoperative
Primary	Interincisal distance	Distance between upper and lower teeth will be measured in mm by ruler	I day postoperative
Primary	Interincisal distance	Distance between upper and lower teeth will be measured in mm by ruler	3rd day postoperative
Primary	Interincisal distance	Distance between upper and lower teeth will be measured in mm by ruler	7th day postoperative
Primary	Edema	Measured from angle of mandible to angle of mouth	Preoperative
Primary	Edema	Measured from angle of mandible to angle of mouth	1day postoperative
Primary	Edema	Measured from angle of mandible to angle of mouth in mm by ruler	2nd day postoperative
Primary	Edema	Measured from angle of mandible to angle hof mouth in mm by ruler	3rd day postoperative
Primary	Edema	Measured from angle of mandible to angle of mouth in mm by ruler	7th day postoperative