Immunotherapy Clinical Trial
Official title:
A Phase II, Multicenter, Randomized Study of Durvalumab and Lenvatinib With or Without Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer
Explore the impact of the first-line application of Durvalumab combined with Lenvatinib, with or without chemotherapy, on the survival, disease progression, and drug safety of patients with advanced biliary tract cancers.
This trial is a two-arm, randomized, multi-center phase II clinical study. Eligible subjects who meet the study criteria will be screened and randomized in a 1:1 ratio to receive treatment with intravenous infusion of Durvalumab combined with oral lenvatinib, with or without chemotherapy. The investigators will closely follow up and assess the efficacy and safety of the combined treatment, evaluate the progression-free survival of the subjects until progression occurs, and observe their overall survival as a secondary outcome. ;
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