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Clinical Trial Summary

This is a prospective observational study of MIPD in clinical practice for paediatric kidney transplant patients using tacrolimus and mycophenolic acid in Radboudumc. Dose individualization in paediatric kidney transplant patients using the InsightRX platform is performed as standard care, meaning that a pharmacokinetic model and drug levels measured at t=0, t=1 and t=2 hours will be used to calculate the exposure. Based on the estimated exposure, the pharmacist gives a dose recommendation to the physician, who can then modify the dosage of mycophenolic acid or tacrolimus. The selected dose and the measured MPA and tacrolimus concentrations will be used to predict the future exposure. A second exposure measurement will be performed to evaluate whether our model is able to predict future exposure.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06095895
Study type Observational
Source Radboud University Medical Center
Contact Astrid Heida, Msc
Phone +31 6 50026019
Email astrid.heida@radboudumc.nl
Status Not yet recruiting
Phase
Start date November 15, 2023
Completion date February 15, 2025

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