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Immunoreconstitution clinical trials

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NCT ID: NCT02274662 Approved for marketing - Immunodeficiency Clinical Trials

Expanded Access Protocol Thymus Transplantation

Start date: n/a
Phase:
Study type: Expanded Access

The primary purpose is to provide access for patients who have immunodeficiency or severe autoimmune disease related to poor thymic function to cultured thymus tissue for implantation. With no thymus function, bone marrow stem cells do not develop into educated T cells, which fight infection. Eligible participants receive cultured thymus tissue for implantation and may undergo biopsy. Immune suppression may be given depending on the immune status and clinical condition of the participant. Immune function testing is continued for one year post-implantation.