Immunocompromised Clinical Trial
Official title:
A Phase II Study to Evaluate the Immunogenicity, Safety and Tolerability of a H1N1 Influenza Vaccine in Immunocompromised Adults Who Have Undergone Solid Organ Transplantation or Bone Marrow Transplantation and in Age-Matched Healthy Volunteers
The trial investigates the efficacy of the adjuvanted H1N1 influenza vaccine Focetria(R) in immunocompromised adults who have undergone solid organ or bone marrow transplantation. It is expected that when administered twice the vaccine fulfills all serological efficacy criteria required for the elderly population age 60 years and older.
n/a
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT05074433 -
A Study to Evaluate Efficacy and Safety of Casirivimab+Imdevimab (Monoclonal Antibodies) for Prevention of COVID-19 in Immunocompromised Adolescents and Adults
|
Phase 3 | |
| Completed |
NCT01258023 -
Seasonal Flu Vaccine in Adult Transplant Recipients
|
Phase 2 | |
| Recruiting |
NCT03808922 -
Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study
|
Phase 3 | |
| Completed |
NCT03262584 -
Evaluation of NGS for Detection and Follow-up of Fungal Pathogens in Immunocompromised Pediatric Patients
|
||
| Recruiting |
NCT01301755 -
Diagnosis of Invasive Pulmonary Aspergillosis by Direct Lung Tissue Aspergillus Galactomannan Antigen Detection From Aspirate by Ultrasound-guided Fine Needle Aspiration
|
N/A | |
| Recruiting |
NCT03425526 -
Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease
|
Phase 1 | |
| Terminated |
NCT02057289 -
A Pharmacokinetic Study of Pediatric Micafungin Prophylaxis
|
Phase 1 | |
| Active, not recruiting |
NCT03168815 -
Low-Flow vs. High-Flow Nasal Cannula for Hypoxemic Immunocompromised Patients During Diagnostic Bronchoscopy
|
N/A | |
| Withdrawn |
NCT05545319 -
A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19
|
Phase 2 | |
| Completed |
NCT05020145 -
COVID-19 Vaccination and Breakthrough Infections Among Persons With Immunocompromising Conditions in the United States
|