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Efficacy of Rapamycin Therapy With Chronic Immune Thrombocytopenia — ITP  

Immune Thrombocytopenic Purpura Clinical Trial

Official title:
Efficacy of Rapamycin Therapy With Chronic Immune Thrombocytopenia

Clinical Trial Summary

The aim of our study is to evaluate the efficacy of rapamycin with Refractory Immune Thrombocytopenic Purpura (RITP) and explore the further mechanism.

Clinical Trial Description

Rapamycin, an immunosuppressive drug, is widely used to prevent allograft rejection and autoimmune diseases. Many studies have shown that the drug contributes to the expansion of regulatory T cells and preserves the highly suppressive function of autoreactive T cells. Patients with RITP often display a decreased proportion of regulatory T cells by flow cytometer, therefore, the investigators will examine the efficacy of rapamycin in RITP patients. ;

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01672151
Study type Observational
Source First Affiliated Hospital of Suzhou Medical College
Contact
Status Completed
Phase N/A
Start date November 2011
Completion date August 2012
View Details
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