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The Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMPL-523 in Immune Thrombocytopenia Patients

Immune Thrombocytopenia (ITP) Clinical Trial

Official title:
The Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMPL-523, a Syk Inhibitor in Adult Patients of Immune Thrombocytopenia: a Randomized, Double Blinded, Placebo Controlled Phase Ib Study

Clinical Trial Summary

This is a randomized, double blinded, placebo-controlled phase Ib clinical trial in adult patients with immune thrombocytopenia. Cross-over treatment will be allowed during the study.

Clinical Trial Description

Approximate 51 to 60 patients will be enrolled in dose escalation (3 cohorts, 8-20 subjects each with the ratio of 3:1 vs Placebo) . ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03951623
Study type Interventional
Source Hutchison Medipharma Limited
Contact jiayi Mai
Phone 086-021-20673063
Email Jiayim@hmplglobal.com
Status Recruiting
Phase Phase 1
Start date August 12, 2019
Completion date December 31, 2021
View Details
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