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Relationship of Endoplasmic Reticulum Stress and Tonsillar Tissue Diseases

Immune System Diseases Clinical Trial

Official title:
Possible Relationship Between Apoptosis and Endoplasmic Reticulum Stress in the Etiopathogenesis of Chronic Tonsillitis and Tonsillar Hypertrophy

Clinical Trial Summary

Tonsillar tissue is a significant organ for the performing of immune systems in children. The Endoplasmic Reticulum (ER), is an organelle needed for the care of a stable function of the cells. The purpose of the study was to explore the correlation among ER stress and tonsillar tissue disorders and to explain the structure of diseases related to the immune system.

Clinical Trial Description

A prospective study was conducted on 46 children aged who underwent tonsillectomy for chronic tonsillitis or tonsil hypertrophy. Tonsil tissues were evaluated in terms of ER stress markers and apoptosis markers by Real-time PCR and Western blot methods. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04653376
Study type Observational
Source Selcuk University
Contact
Status Completed
Phase
Start date November 1, 2018
Completion date June 10, 2019
View Details
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