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Clinical Trial Summary

The purpose of this study is to clarify the changes of neurocognitive function of patients undergoing cardiac valve disease before and after surgical treatment under cardiopulmonary bypass operation, and to predict the neurological prognosis of such patients through combined imaging technology, so as to improve and avoid the occurrence of postoperative neurological dysfunction in such patients.


Clinical Trial Description

This study focuses on brain protection in patients with heart disease. The preoperative brain imaging and consciousness and cognition evaluation results, intraoperative brain monitoring indicators, adverse events of neurological function, brain imaging and consciousness and cognition evaluation results during the postoperative and follow-up periods were recorded. At the same time, serum markers related to perioperative neurological function were obtained to explore the relevant factors affecting neurocognitive function during the perioperative period. The research objectives to investigate the perioperative changes of neurocognitive function in patients undergoing heart valve surgery under cardiopulmonary bypass and the related factors affecting the prognosis of neurocognitive function. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05539261
Study type Observational [Patient Registry]
Source Nanjing University of Traditional Chinese Medicine
Contact Nengrui Guo
Phone 0086-17635599999
Email 657040251@qq.com
Status Not yet recruiting
Phase
Start date September 10, 2022
Completion date December 31, 2025

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