Clinical Trial Details
— Status: Recruiting
Administrative data
NCT number |
NCT05622565 |
Other study ID # |
2021KYPJ164 |
Secondary ID |
|
Status |
Recruiting |
Phase |
|
First received |
|
Last updated |
|
Start date |
January 2011 |
Est. completion date |
July 2024 |
Study information
Verified date |
July 2023 |
Source |
Sun Yat-sen University |
Contact |
Yingfeng Zheng, M.D. Ph.D |
Phone |
+8613922286455 |
Email |
zhyfeng[@]mail.sysu.edu.cn |
Is FDA regulated |
No |
Health authority |
|
Study type |
Observational
|
Clinical Trial Summary
To establish a deep learning system of various ocular fundus disease analytics based on the
results of multimodal examination images. The system can analyze multimodal ocular fundus
images, make diagnoses and generate corresponding reports.
Description:
The ocular fundus is the only part of the human body that can directly see the blood vessel
microcirculation and nerve tissue. Through various imaging tests, including Color Fundus
Photograph (CFP), Optical Coherence Tomography (OCT), Fluorescein Fundus Angiography (FFA)
and Indocyanine Green Angiography (ICGA), etc., it is possible to statically overview or
dynamically observe the retina and choroid, the condition of blood vessels and nerves, and
comprehensive diagnosis of the disease. The screening, interpreting and accurate diagnosis of
ocular fundus diseases are crucial for disease prevention, control and precise treatment.
However, due to the variety of fundus examination methods, and the complexity and
professionalism of the examination, there is a lack of fundus specialists who have sufficient
clinical experience and knowledge to interpret fundus examinations. With the continuous
development of artificial intelligence (AI) in diagnosing fundus diseases, various modalities
of imaging examination methods are gradually applied to the development of fundus disease
diagnosis systems. Moreover, medical images often come with corresponding reports, which are
mostly generated by clinicians' or radiologists' experience.
Here, we are establishing a fundus disease diagnosis and report-generating system based on
cross-modal ocular fundus imaging examinations, and fundus lesions were visualized at the
same time. Multi-center data verification will also be conducted. The results of the research
will assist in fundus lesions diagnosis and imaging reports generation. We hope this could
popularize more complex fundus imaging examination methods to society, and help improve the
early diagnosis and treatment of fundus lesions that cause blindness.