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Ileostomy - Stoma clinical trials

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NCT ID: NCT03746353 Terminated - Colonic Neoplasms Clinical Trials

Early Closure Versus Conventional Closure in Postoperative Patients With Low Anteriresection for Rectal Cancer

Start date: September 5, 2018
Phase: N/A
Study type: Interventional

Colorectal cancer worldwide is the third most common in men and the second in female, although mortality is not as high as its incidence, there is less survival in developing countries. According to data from the World Health Organization, in 2012, there were an estimated 1.4 million cases and 693,900 deaths from this disease. Patients with rectal cancer are frequently taken to resection surgery as a curative management of their malignant pathology, according to the type of resection or reconstruction. In a high number of cases, they are management with colorectal anastomosis with a derivative ileostomy in the same procedure. The closure of this ileostomy is usually done after two to three months of the procedure, however in our environment it could take up to six or twelve months, during which time the patient is exposed to social difficulties, management problems and complications, derived from it. The early closure (7-12 days of its creation) of an ileostomy, despite the little evidence, seems to be a safe, feasible procedure that would save the patient having to live temporarily with an ileostomy.

NCT ID: NCT03587519 Terminated - Ulcerative Colitis Clinical Trials

Short Versus Long Interval to Ileostomy Reversal After Ileal Pouch Surgery

SLIRPS
Start date: November 6, 2018
Phase: N/A
Study type: Interventional

In patients with ulcerative or indeterminate colitis who undergo ileal pouch anal anastomosis and diverting loop ileostomy (IPAA) surgery* a short interval to loop ileostomy reversal will result in differences in complications and quality of life compared to a long interval to loop ileostomy reversal.

NCT ID: NCT03451253 Terminated - Clinical trials for Inflammatory Bowel Diseases

Effects of an Amino Acid Mixture on Gastrointestinal Function, Inflammation and Fluid Balance: A Pilot Study in Patients With Inflammatory Bowel Disease

Start date: April 12, 2018
Phase: N/A
Study type: Interventional

This pilot study will examine the benefit of this amino acid based hydration solution in patients with IBD who have undergone a total colectomy and have either ileostomies or jpouches. Findings from this study and possible future studies could have broad implications for patients with malabsorption resulting from many underlying conditions, including IBD.

NCT ID: NCT03424954 Terminated - Ileostomy - Stoma Clinical Trials

The Effect of a 30-day Automated Text Messaging Intervention on Hospital Based Acute Care Encounters Following Ileostomy

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

Each year a large number of patients undergo ileostomy surgery, a procedure in which a portion of the small intestine is attached to a hole in the abdominal wall, allowing for digested material to pass into a disposable bag worn attached to the skin. Ileostomies are performed for the treatment of a variety of diseases of the intestinal tract, such as inflammatory bowel disease, intestinal trauma, and gastrointestinal malignancy. Of the patients that undergo ileostomy surgery, 36% will require urgent medical care within the first 30 days of surgery. Most frequently, this is a result of dehydration due to excessive ostomy output. Thus, there is potential for significant improvement of the post-operative outcomes of ileostomy patients. Implementation of an automated text messaging system, EpxOstomy, can provide a way of monitoring patient's daily ostomy output and allow for timely intervention if output is outside normal limits, providing an effective way of improving patient outcomes while simultaneously reducing healthcare costs.

NCT ID: NCT03416023 Terminated - Ileostomy - Stoma Clinical Trials

Safety, Performance and Durability of the TIES® Implant in Patients Requiring a Permanent Ileostomy

Start date: October 30, 2018
Phase: N/A
Study type: Interventional

Study to assess the safety, performance and durability of the TIES® transcutaneous titanium implant in patients requiring a permanent ileostomy.

NCT ID: NCT02694757 Terminated - Ileostomy - Stoma Clinical Trials

Efficacy of Ostom-i Alert System at Decreasing Dehydration Related Complications

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy of the Ostom-i device in decreasing readmission rates of subjects with new ileostomies in the first 30 days post-operatively.

NCT ID: NCT01994863 Terminated - Ileostomy - Stoma Clinical Trials

Safety and Performance Investigation of a New 1-piece Ostomy Product Compared to Standard of Care 1-piece in Subjects With Ileostomy

Start date: September 2012
Phase: Phase 2
Study type: Interventional

The objective of the investigation is to document New Mio 1-piece is non-inferior (no worse) in reducing leakage (4-point scale) compared to Standard of Care.

NCT ID: NCT01411917 Terminated - Ileostomy - Stoma Clinical Trials

Transversus Abdominis Plane Blocks for Ileostomy Takedown: A Prospective Study

Start date: August 2011
Phase: N/A
Study type: Interventional

Consenting subjects will be randomized to receive injection of bupivacaine or placebo before surgery for ileostomy takedown (injection administered after general anesthesia has been administered). Pain and side effects will be assessed periodically after surgery using the verbal Numeric Rating pain Scores, including at the timepoint of 24 hours after surgery. All subjects in this study will be given toradol to ensure adequate pain control.