Effect-site Concentration of Propofol for I-gel Insertion During Anesthesia Induction With a Single-dose Dexmedetomidine

Igel Clinical Trial

— D-pofol  

Official title:

Preducted Effect-site Concentration of Propofol for I-gel Insertion During Anesthesia Induction

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02268656
• Other study ID #: GCIRB2014-153
• Status: Completed
• Phase: N/A
• Start date: October 2014
• Est. completion date: February 2015

Study information

• Verified date: August 2022
• Source: Gachon University Gil Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Before anethetic induction, infuse dexmedetomidine 0.5 mcg/kg for 2 minutes and after injection of lidocaine 30 mg, propofol infusion by using target controlled infusion (TCI) pump. Effect site concentraion of propofol start from 5 and changes the concentration as previous response to i-gel insertion as up and down methods

Description:

Before anethetic induction, infuse dexmedetomidine 0.5 mcg/kg for 2 minutes and after injection of lidocaine 30 mg, propofol infusion by using target controlled infusion (TCI) pump. Effect site concentraion of propofol start from 5 and changes the concentration as previous response to i-gel insertion as up and down methods. Failure of previous subjects are defined as difficulty to mouth open, severe nausea and couph and laryngeal spasm, and not loss of consciousness.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: February 2015
• Est. primary completion date: February 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

• ASA PS I-II, 20-60 yrs old

Exclusion Criteria:

• predicted difficulty airway, recent URI, BMI > 30kg/m2, reactive airway disease

Related Conditions & MeSH terms

• Igel

Intervention

Drug:
• propofol concentration
First subjects start from effect site concentraion of 5ug/ml propofol, after insertion of i-gel, determine the next subjects' effect site concentraion would be increae or decrease 0.5 ug/ml as up and down method

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Gachon University Gil Medical Center

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Concentration of Propofol	effect site concentration of propofol	from i-gel insertion up to 5 min