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Supportive Versus Immunosuppressive Therapy for the Treatment Of Progressive IgA Nephropathy — STOP-IgAN  

IgA Nephropathy Clinical Trial

Official title:
Supportive Versus Immunosuppressive Therapy for the Treatment Of Progressive IgA Nephropathy

Clinical Trial Summary

- Evaluation of the efficacy of an immunosuppressive therapy added to a comprehensive supportive therapy to induce a clinical remission in patients at risk for progressive IgAN

- Investigation of differences between the treatments regarding the number of patients loosing more than 15 ml/min of GFR.

Clinical Trial Description

The best treatment of glomerular diseases of the kidney is currently not well defined. This study aims to answer if in patients with IgA nephropathy, the most common type of glomerulonephritis an immunosuppressive treatment (with the use of steroids and chemotherapy) added to a supportive treatment is more effective than a supportive treatment alone (with the use of drugs lowering the blood pressure and the urinary protein loss). ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00554502
Study type Interventional
Source RWTH Aachen University
Contact
Status Completed
Phase Phase 3
Start date February 2008
Completion date February 2015
View Details
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