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IgA Nephropathy (IgAN) clinical trials

View clinical trials related to IgA Nephropathy (IgAN).

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NCT ID: NCT03841448 Terminated - Clinical trials for Glomerulonephritis, IgA

A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN)

Start date: September 30, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effect of cemdisiran on proteinuria in adults with immunoglobulin A nephropathy (IgAN), who excrete >1 gram (gm) of protein per day despite standard of care, which includes treatment with angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARB). These participants are at high risk for progression of kidney disease, which can result in end-stage renal failure.