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NCT03398031 Clinical Trial

Effect of Magnesium Supplement in Early Pregnancy After ICSI

ICSI Clinical Trial

Official title:
Magnesium Supplement in Early Pregnancy After ICSI

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT03398031
Other study ID # ashams university
Secondary ID
Status Recruiting
Phase Phase 3
First received January 6, 2018
Last updated January 6, 2018
Start date June 1, 2017
Est. completion date June 1, 2018

Study information
Verified date January 2018
Source Ain Shams University
Contact Radwa R Ali, MD
Phone 01283492979
Email radwaebed@yahoo.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Daily supplement of magnesium after biochemical diagnosis of pregnancy in females pregnant after ICSI and through out 1st trimester

Description:

a fall of magnesium levels at 2-3 weeks of gestation. This drop of magnesium concentration is larger following IVF as compared to spontaneous pregnancies.

so magnesium supplement start after biochemical diagnosis of pregnancy and throughout the 1st trimester

Recruitment information / eligibility
Status Recruiting
Enrollment 180
Est. completion date June 1, 2018
Est. primary completion date March 1, 2018
Accepts healthy volunteers No
Gender Female
Age group 25 Years to 35 Years
Eligibility Inclusion Criteria:

- age 25_38 years

- BMI 25_30

- females pregnant after ICSI after biochemical diagnosis of pregnancy

Exclusion Criteria:

- females with poor ovarian reserve and poor responders

- abnormality in uterine cavity detected by hysteroscopic evaluation pre ICSI and not treated

- hydrosalpinx

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Magnesium Oxide
After biochemical diagnosis of pregnancy each participant will receive magnesium plus 500 mg tablet once daily till the end of the 1st trimester
• Placebo Oral Tablet
After biochemical diagnosis of pregnancy each participant will receive placebo tablet once daily till the end of the 1st trimester

Locations
Country Name City State
Egypt AinShams university maternity hospital Cairo Abbassya

Sponsors (1)
Lead Sponsor Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary 1st trimesteric abortion Either spontaneous or missed abortion 13 week of gestation
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