IBD Clinical Trial - Combination Therapy With Two Biologicals

Status Completed

Clinical Trial Summary

The efficacy and safety of dual biological therapy.

Clinical Trial Description

Data of all patients treated with the combination of two biologicals in four Finnish tertiary centres were collected and analysed. Inclusion criteria were simultaneous use of two biological treatments (infliximab, adalimumab, golimumab, vedolizumab or ustekinumab), age 16 years or over and follow-up for at least induction period after introduction of second biological therapy. The primary outcome was effectiveness, defined as remission assessed by physician after at least four months of DBT. The secondary outcome was safety defined by any adverse events or infection complications during DBT. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05135221
Study type	Observational [Patient Registry]
Source	Tampere University Hospital
Contact
Status	Completed
Phase
Start date	January 1, 2015
Completion date	October 1, 2021

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Combination Therapy With Two Biologicals — Combi

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms