Hysteroscopy Clinical Trial
Official title:
Oral Tramadol Versus Oral Dexketoprofen for Reducing Pain During Office Hysteroscopy in Post Menopausal Women
Two hundreds and twenty five postmenopausal women undergoing outpatient hysteroscopy and endometrial biopsy will be randomly divided into three equal groups. To ensure blinding the investigators will use the double dummy technique in which group 1 will receive Tramadol 100mg (Trama®, Global Napi, Giza, Egypt) orally in addition to a placebo similar to Celecoxib, group 2 will receive dexketoprofen 25mg (neo ketadex 25, Marcryl, Egypt) in addition to a placebo similar to Tramadol, and group 3 will received a placebo similar to Tramadol and a placebo similar to Celecoxib. All drugs will be given 2 hours before the procedure. An independent person will generate the allocation sequence using computer generated random numbers.
Two hundreds and twenty five postmenopausal women undergoing outpatient hysteroscopy and
endometrial biopsy will be randomly divided into three equal groups. To ensure blinding the
investigators will use the double dummy technique in which group 1 will receive Tramadol
100mg (Trama®, Global Napi, Giza, Egypt) orally in addition to a placebo similar to
Celecoxib, group 2 will receive dexketoprofen 25mg (neo ketadex 25, Marcryl, Egypt) in
addition to a placebo similar to Tramadol, and group 3 will received a placebo similar to
Tramadol and a placebo similar to Celecoxib. All drugs will be given 2 hours before the
procedure. An independent person will generate the allocation sequence using computer
generated random numbers.
Statistics:
Quantitative data will be statistically represented in terms of mean ± standard deviation (±
SD) while categorical data will be represented as frequency and percentage. Comparison of
quantitative data will be done using ANOVA test for independent samples while categorical
data will be compared using Chi squared test or Fisher exact test when appropriate. A
probability value (p value) less than 0.05 will be considered significant.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05514236 -
Effect of Virtual Reality and Music Therapy on Pain Relief in Outpatient Hysteroscopy
|
N/A | |
| Recruiting |
NCT06092541 -
Pericervical Analgesia Versus Analesia With Nitrous Oxide (N2O) in Outpatien Operative Hysteroscopy With Miniresector
|
N/A | |
| Not yet recruiting |
NCT05069077 -
the Effect of Music on Pain and Women Satisfaction During Diagnostic Outpatient Hysteroscopy in Postmenopausal Women
|
N/A | |
| Completed |
NCT03701984 -
The Effect of Intrauterine Lidocaine Infusion and Oral Tramadol on Pain During Diagnostic Office Hysteroscopy
|
Phase 4 | |
| Not yet recruiting |
NCT05069025 -
Use of Music in Reducing Pain During Outpatient Hysteroscopy in Primarily Infertile Patients
|
N/A | |
| Completed |
NCT04166500 -
Early Outpatient Hysteroscopy Can Prevent Intrauterine Adhesion After Induced Abortion
|
N/A | |
| Completed |
NCT02863679 -
Postoperative Analgesic Efficacy of Tetracaine Hydrochloride Gel
|
N/A | |
| Completed |
NCT02142673 -
The Impact of Different Filling Pressures in Operative Outpatient Hysteroscopy on the Procedure Success Rates and Associated Pain.
|
N/A | |
| Completed |
NCT02142686 -
Comparison Between Different Filling Pressures in Diagnostic Outpatient Hysteroscopy
|
N/A | |
| Completed |
NCT05540379 -
Role of Virtual Reality Simulators in Basic Hysteroscopy Training Competence
|
N/A | |
| Completed |
NCT04462835 -
Feasibility, Effectiveness and Safety of Outpatient Hysteroscopy
|
||
| Recruiting |
NCT04862598 -
Virtual Reality to Improve Satisfaction in Hysteroscopy Patients
|
N/A | |
| Recruiting |
NCT01376934 -
Clinical Trial of Hysteroscopy in Postmenopausal Women to Compare Techniques
|
N/A | |
| Not yet recruiting |
NCT06172140 -
Efficacy and Safety of Ciprofol for the Sedation in Patients Undergoing Hysteroscopy
|
N/A | |
| Recruiting |
NCT03409835 -
Effect of Ramosetron on Post-discharge Nausea and Vomiting
|
N/A | |
| Enrolling by invitation |
NCT03579550 -
Hysteroscopic Metroplasty in Unexplained Infertile Women With Dysmorphic Uterus
|
N/A | |
| Recruiting |
NCT02736019 -
Tramadol Versus Celecoxib for Reducing Pain During Office Hysteroscopy in Post Menopausal Women
|
Phase 3 | |
| Recruiting |
NCT02736071 -
Tramadol Versus Celecoxib for Reducing Pain During Operative Office Hysteroscopy
|
Phase 3 | |
| Not yet recruiting |
NCT05858931 -
Hysteroscopic Evaluation and the Clinical Outcomes of Vaginal Repair of Cesarean Section Scar Defects
|
||
| Completed |
NCT04232930 -
The Use of Music in Reducing Pain During Outpatient Hysteroscopy
|
N/A |