Clinical Trials Logo

Clinical Trial Summary

The aim of this study is to estimate whether the use of the barbed suture facilitates laparoscopic suturing of the vaginal cuff during total laparoscopic hysterectomy.

Clinical Trial Description

Vaginal cuff suturing is a significant step during hysterectomy with regard to operating time and a critical passage for the risk of vaginal cuff dehiscence. Vaginal cuff dehiscence is a severe adverse event and occurs more frequently after total laparoscopic hysterectomy (0.3-3.1 %) compared to abdominal and vaginal hysterectomy

Barbed suture is a new type of sutures introduced to facilitate laparoscopic suturing.When compared with conventional smooth suture, barbed suture has external barbs that anchor the suture to the tissues and prevent the retrograde movement of suture thread during suturing. Consequently, laparoscopic suturing can be performed easily without the need for suture locking, without applying traction on suture thread by the assistant and without tying knots at both ends of the suture line In gynecology, barbed sutures have been used in minimally invasive ,myomectomy hysterectomy, ovarian cystectomy and sacrocolpopexy. There is a growing body of evidence that the use of barbed sutures in these procedures facilitates laparoscopic suturing and significantly reduces suturing time, total operating time and intraoperative blood loss To date only two small randomized controlled trials compared the effectiveness of the bidirectional knotless barbed suture versus standard suture in the repair of vaginal cuff ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

NCT number NCT02998658
Study type Interventional
Source Cairo University
Contact Usama M Fouda, Prof.
Email [email protected]
Status Not yet recruiting
Phase Phase 2
Start date February 2017
Completion date February 2019

See also
  Status Clinical Trial Phase
Recruiting NCT04130464 - Intraperitoneal Infusion of Analgesic for Postoperative Pain Management Phase 4
Completed NCT04080323 - Single-dose Vaginal Dinoprostone and Hysterectomy Phase 3
Completed NCT03187327 - Feasibility of Opportunistic Salpingectomy at the Time of Vaginal Hysterectomy for Benign Pathology N/A
Completed NCT00528177 - Morphine vs. Oxycodone for Postoperative Pain Management Phase 4
Terminated NCT00551785 - Surveillance Study of Women Taking Intrinsa® Phase 4
Completed NCT03641625 - Effect of SmtO2 Guided Care on PONV (iMODIPONV) N/A
Recruiting NCT03500744 - Erector Spinae Plane Block for Major Gynecologic and Urologic Surgery Phase 2/Phase 3
Recruiting NCT03294343 - Risk-Reducing Surgeries for Hereditary Ovarian Cancer N/A
Completed NCT03610425 - A Standardized Bundle Protocol to Optimize Outcomes With Patients Undergoing Gynecological Surgery
Completed NCT03634306 - Ultravision Visual Clearing System in Laparoscopic Hysterectomy and Myomectomy N/A
Completed NCT01526668 - Follow-up Strategies for Improved Postoperative Recovery After Benign Hysterectomy N/A
Recruiting NCT04109989 - Clinical Assessment - HominisTM Surgical System N/A
Recruiting NCT03776838 - Impact of Nociceptive-Level (NOL) Intraoperative Guided Analgesia During Gynecological Laparoscopic Surgery Under General Anesthesia Phase 4
Recruiting NCT02911831 - IV Tranexamic Acid Prior to Hysterectomy Early Phase 1
Completed NCT02276261 - The Effect of Vertical Versus Horizontal Vaginal Cuff Closure on Vaginal Length After Laparoscopic Hysterectomy N/A
Completed NCT01933139 - Informed Consent for Hysterectomy: Effectiveness of Audio-visual Presentations on Patient Comprehension N/A
Completed NCT01182714 - A Prospective Randomized Control Trial Comparing Immediate and 24-hours Delayed Catheter Removal Following Hysterectomy N/A
Completed NCT00399568 - Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery Phase 3
Recruiting NCT03363425 - Effect of Perioperative iv Dexmedetomidine vs. Lidocaine on Postoperative Pain, Analgesic Consumption and Recovery After Abdominal Gynaecological Surgery Phase 2/Phase 3
Not yet recruiting NCT04886791 - Vaginal NOTES Hysterectomy Versus Vaginal Hysterectomy N/A