Clinical Trials Logo

Hysterectomy clinical trials

View clinical trials related to Hysterectomy.

Filter by:

NCT ID: NCT06455540 Not yet recruiting - Hysterectomy Clinical Trials

SUperior Hypogastric Plexus Block During Laparoscopic hysterEctomy (SUBTLE)

SUBTLE
Start date: July 16, 2024
Phase: N/A
Study type: Interventional

This trial sest to assess the efficacy of a superior hypogastric plexus block (SHPB) for quality of recovery after a laparoscopic hysterectomy.

NCT ID: NCT06340776 Completed - Vomiting Clinical Trials

The Effects of Acupressure on Pain, and Gastrointestinal Functions in Women With Hysterectomy

Start date: August 15, 2021
Phase: N/A
Study type: Interventional

Aim This randomized controlled trial was conducted to evaluate the effect of acupressure application on gastrointestinal functions and pain after abdominal hysterectomy. Materials and methods After undergoing hysterectomy, 39 women were randomised into acupressure (n=19), and control groups (n=20). Women in the acupressure group received acupressure on the mide meridian (ST36), the heart meridian (HT7), large intestine meridian (LI4), intersection of the spleen, liver and kidney meridians 6(SP6) and pericardium meridian (PC6) acupoints 30 min after admission to the clinic, for a period of 15 min, whereas those in the sham group received acupressure on locations 1-1.5 cm away from these points. The control group received standard treatment. The patient information form, Visual analog scale, the Rhodes Index of Nausea, Vomiting and Retching, and daily follow-up form were used for data collection.

NCT ID: NCT06168578 Active, not recruiting - Hysterectomy Clinical Trials

The Effect of Alveolar Recruitment Manoeuvre on Optic Nerve Sheath Diameter in Laparoscopic Hysterectomies

Start date: January 15, 2024
Phase:
Study type: Observational

Laparoscopic total hysterectomy is the most common gynaecological surgical procedure after caesarean section. In laparoscopic total hysterectomy, intraabdominal pressure increases, venous return decreases, hypercarbia and acidosis may occur due to pneumoperitoneum due to CO2 insufflation and upright trendelenburg position (TP). Cerebral blood flow, intracranial pressure (ICP) and intraocular pressure (IOP) increase. One study showed that TP and an intraabdominal pressure of mmHg significantly increased ICP. CO2 insufflation into the abdominal cavity causes upward displacement of the diaphragm, resulting in an increased risk of regurgitation, decreased lung volumes and compliance, atelectasis, increased airway resistance and ventilation-perfusion mismatch. At the same time, combined with the effects of general anaesthesia, a decrease in partial arterial oxygen pressure (PaO2) is expected in patients. The alveolar recirculation manoeuvre (ARM), is based on the technique of opening atelectatic lung fields by keeping the airway pressure high for a while. This manoeuvre can be performed with methods such as PEEP, CPAP, and pressure-controlled mechanical ventilation. High PEEP application may cause an increase in ICP and a decrease in cerebral perfusion pressure by increasing intrathoracic pressure and decreasing cerebral venous return. Therefore, intracranial pressure monitoring should be performed especially in patients with PEEP above 8-10 cmH2O. Intraventricular and intraparenchymal measurements, which are the gold standard methods for ICP monitoring, are invasive procedures with various risks. Noninvasive methods such as cranial CT, brain MRI, transcranial Doppler, and measurement of optic nerve sheath diameter (ONSD) can also be used for ICP measurement. Ultrasonography of the optic nerve sheath diameter is an increasingly common method because it is noninvasive and can be performed at the bedside. The optic nerve sheath is the continuation of the transverse subarachnoid space and the cerebral duramater. It is connected to the intracranial subarachnoid space with cerebrospinal fluid. Therefore, an increase in ICP increases the optic nerve sheath diameter (ONSD). Maissan et al. They think that ONSD reflects the changes in ICP simultaneously. The aim of this study was to evaluate the effect of ARM on intracranial pressure in patients undergoing total laparoscopic hysterectomy under general anaesthesia using optic nerve sheath diameter.

NCT ID: NCT06138197 Recruiting - Hysterectomy Clinical Trials

Comparison of Three Robotic Platforms for Hysterectomy

COMPAR-HYST
Start date: January 4, 2024
Phase:
Study type: Observational

Hysterectomy is the most common procedure in gynaecology after a cesarean section. In recent years, the laparoscopic approach has become preferred given the different advantages over the traditional laparotomic approach, and both conventional laparoscopy and robotic-assisted laparoscopy have become the standard approach for hysterectomy. To date, robotic-assisted laparoscopic hysterectomy has been performed using one robotic platform and only recently, two new robotic platforms have been introduced in clinical practice. Although all three are registered for human use and available for clinical practice, there are currently not enough clinical experiences and data in the literature to evaluate the efficacy, safety and relationship between cost and efficacy of the new platforms available for the robotic-assisted laparoscopic hysterectomy. For this reason, the investigators will conduct an exploratory clinical study on a Post Market Clinical Follow up (PMCF) medical device aimed at performing a preliminary assessment of the global performance of the ITL procedure implemented using the three robotic platforms currently available.

NCT ID: NCT06039566 Recruiting - Hysterectomy Clinical Trials

NAC vs Placebo on Opioid Use for Hysterectomy

Start date: November 30, 2023
Phase: Phase 3
Study type: Interventional

This study will enroll females who are ages 18 and older undergoing a laparoscopic or robotic, partial or full hysterectomy. Participants will be randomized to receive IV n-acetylcysteine or placebo during the first 60 minutes of their procedure. At various time points after the procedure patients will be asked to report their pain scores, and any pain medication taken.

NCT ID: NCT06011538 Not yet recruiting - Hysterectomy Clinical Trials

Web-based Versus Standard Information for Same Day Hysterectomy (WISH)

WISH
Start date: September 2023
Phase: N/A
Study type: Interventional

Objectives: To evaluate the potential utility and efficacy of additional on-line, patient education resource for same day discharge following laparoscopic hysterectomy (SDD LH) compared to standard information resources alone Trial Design: A pilot, parallel, open, single centre, randomised controlled trial Participant Population and Sample Size: 40 women undergoing SDD LH for a benign reason Eligibility Criteria: Women with gynaecological conditions requiring a laparoscopic hysterectomy (LH) and who are suitable for same day discharge (SDD). Interventions: An online patient education website resource and the comparator is standard practice for provision of patient information (written and verbal). Outcome Measures: Primary - Compliance with SDD Secondary - In Hospital: o Surgical details / complexity / intraoperative and post-operative serious adverse events (SAEs) according to the Clavien-Dindo system grade II-IV which is a widely used index for the classification of surgical complications [case notes and electronic patient record], and time to discharge - 6 weeks: - Satisfaction, acceptability and utility of patient education / information provided (bespoke patient questionnaire; Likert scales) - Satisfaction with care after LH (6-point Likert) - Generic quality of life at 6 weeks post-surgery (EuroQol-5D-5L and VAS); - Contact with Community & Clinical Care Services i.e. outpatients or emergency visits, re-presentations / re-admissions to hospital (Case report form [CRF], case notes, electronic patient record) - Serious Adverse Events (CRF, case notes, electronic patient record) - Time from surgery to resumption of usual activities using the PROMIS-SF (Patient-Reported Outcomes Measurement Information System Physical Function) questionnaire (Modified items / response categories) - 12 weeks: - Time from surgery to resumption of usual activities using the PROMIS-SF (Patient-Reported Outcomes Measurement Information System Physical Function) questionnaire (Modified items / response categories) Time to return to work (if working)

NCT ID: NCT05959785 Recruiting - Hysterectomy Clinical Trials

Diaphragmatic Exercises as Treatment of Referred Pain After Total Laparoscopic Hysterectomy: Randomized Clinical Trial.

Start date: July 17, 2023
Phase: N/A
Study type: Interventional

Through a blinded clinical trial, the aim is to evaluate the efficacy of manual therapy in the treatment of pain referred to after laparoscopic hysterectomy. Control and intervention groups were randomly established. Informed consent will be requested for participation in the study.

NCT ID: NCT05955651 Recruiting - Hysterectomy Clinical Trials

Prospective Analysis to Detect Myometrial Cells in Peritoneal Washing in Patients Undergoing Minimally Invasive Hysterectomy Using Containment Bag at University of Texas Medical Branch

Start date: August 1, 2023
Phase:
Study type: Observational

The Aim of the study is to determine endometrial/myometrial spillage during total laparoscopic hysterectomy with manual morcellation.

NCT ID: NCT05931354 Recruiting - Clinical trials for Cervical Intraepithelial Neoplasia

Longitudinal HPV Pap in CIN and VAIN

LHPCV
Start date: July 1, 2017
Phase:
Study type: Observational

This study will construct a longitudinal risk model of VaIN according to the HPVs distribution of cervix and vaginal for those had CIN2+. The study will include three arms to complete the follow-up data for the previous cohort constructed, and prospectively recruit new subjects with the appropriate inclusion/excluding criteria in order to increase sample size of this study.

NCT ID: NCT05681910 Recruiting - Hysterectomy Clinical Trials

Mode of Uterine Extraction in Total Laparoscopic Hysterectomy

Start date: January 2023
Phase:
Study type: Observational

Hysterectomy remains the most common major gynecological operation worldwide. It may be carried out by three different routes and its variations: vaginal, abdominal, and laparoscopic. A large uterus will lead to several surgical difficulties during laparoscopic hysterectomy, such as limited operative field, restrictive instrument range of motion, and difficult removal of the specimen. The aim of this study was to compare the clinical results of TLH for large uterus through transvaginal or uterine morcellation approaches after strict preoperative assessment.