Xenon and Cooling Therapy in Babies at High Risk of Brain Injury Following Poor Condition at Birth — CoolXenon3

Hypoxic Ischaemic Encephalopathy Clinical Trial

Official title:
Xenon and Cooling Therapy in Babies at High Risk of Brain Injury Following Poor Condition at Birth: A Randomised Pilot Outcomes Study (COOLXENON3 Study)

Status Completed

Clinical Trial Summary

This study examines the effect of inhaled xenon gas in the treatment of newborn infants with hypoxic-ischemic encephalopathy (HIE) in combination with cooling, which is the standard treatment for this condition. The hypothesis is that the xenon + cooling combination will produce better neuroprotection than the standard treatment of cooling alone.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02071394
Study type	Interventional
Source	University Hospitals Bristol and Weston NHS Foundation Trust
Contact
Status	Completed
Phase	Phase 2
Start date	March 2014
Completion date	April 15, 2020

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See also
Status	Clinical Trial	Phase
Completed	`NCT01545271` - Xenon and Cooling Therapy in Babies at High Risk of Brain Injury Following Poor Condition at Birth	Phase 1/Phase 2
Completed	`NCT02800018` - Correlation of Risk Factors and Severity of Hypoxic-ischaemic Encephalopathy
Completed	`NCT00934700` - Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal Asphyxia	N/A