Clinical Trials Logo

Clinical Trial Summary

This study will compare the ability of pulsed-dose oxygen from a concentrator to reverse altitude-induced hypoxemia compared to compressed gas from a standard oxygen cylinder.


Clinical Trial Description

Subjects will be monitored non-invasively with pulse oximetry, end-tidal carbon dioxide, tissue oxygenation and ECG. The mean seal level oxygen saturation will be recorded.Subjects exposed to an altitude of 14,000 feet will experience moderate hypobaric hypoxia. The mean oxygen saturation at this altitude is 83%. Subjects will receive oxygen from both an oxygen concentrator or a cylinder of oxygen following exposure to hypobarism. Oxygen from each source will be increased in 1 liter per minute increments until the oxygen saturation returns to the baseline sea level oxygen saturation.

The oxygen requirement to return oxygen saturation to baseline values will be recorded. The flow from the concentrator and the cylinder will be compared. ;


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01477450
Study type Interventional
Source University of Cincinnati
Contact
Status Completed
Phase N/A
Start date October 2011
Completion date September 2012

See also
  Status Clinical Trial Phase
Suspended NCT03628560 - Alternate Methodology of Pulse Oximeter Validation N/A
Completed NCT02866578 - Open Lung Protective Ventilation in Cardiac Surgery N/A
Recruiting NCT06139081 - Oxygen Delivery Methods of Nasal Catheter on the Incidence of Hypoxemia in Patients With Painless Gastroscopy N/A
Not yet recruiting NCT05964309 - Pre-oxygenation in Sitting Position and Oxygen Reserve Index N/A
Completed NCT00740220 - Reproducibility of 6 Minute Walk Tests for Oxygen Desaturation N/A
Completed NCT00675415 - Does Capnography Prevent Hypoxemia During Endoscopic Retrograde Cholangiopancreatography and Endoscopic Ultrasound? N/A
Completed NCT04557605 - Effects of a Face Mask on Oxygenation During Exercise N/A
Active, not recruiting NCT05479929 - Work of Breathing Assessment in Triage Scale
Recruiting NCT05422430 - Rebreathing-induced Hypoxia and Glucose Levels N/A
Recruiting NCT03009643 - Salvage Treatment of Inhaled Nitric Oxide in Patients With Refractory Hypoxemia After Aortic Surgery N/A
Completed NCT01949012 - Capnography Monitoring During Intravenous Conscious Sedation Sedation With Midazolam for Oral Surgery N/A
Completed NCT01470170 - Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy Phase 4
Recruiting NCT06085859 - Anesthesia Endoscope Mask is Applied to Sedation Upper Gastrointestinal Endoscopic Diagnosis and Treatment N/A
Recruiting NCT03969615 - SuperNO2VA™ and General Anesthesia Postoperative Care N/A
Completed NCT02554110 - Peripheral Nerve Stimulation to Reduce Hypoxic Events N/A
Completed NCT04566419 - poStoperative Anesthesia Care: Facial Mask vs Hfnc and Thoracic Ultrasound for Reduction of Atelectasis Incidence N/A
Completed NCT04998253 - Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction in ARDS Secondary to SARS-CoV2 Early Phase 1
Recruiting NCT04079465 - Automated Oxygen Control by O2matic to Patients Admitted With Acute Hypoxemia N/A
Recruiting NCT06022523 - Accuracy of Pulse Oximeters With Profound Hypoxia N/A
Completed NCT04159116 - Prevention and Treatment of Laryngospasm and Hypoxemia Based on Risk Factors in Adult Outpatients Undergoing EGD N/A